Abstract：
The aim of this case series was to evaluate implants inserted in bone after guided bone regeneration (GBR). Fourteen patients with generalized aggressive periodontitis (GAP) who had lost one or two maxillary teeth in the incisor or premolar region were enrolled in the study. Due to bone resorption, the lateral width and vertical height of the bone were insufficient for implant placement. GBR was carried out in a staged approach using titanium-reinforced e-PTFE (expanded polytetrafluoroethylene) membranes. No bone grafts or bone substitute materials were used. After 6 to 8 months, turned-surface implants (n = 47) were inserted in augmented and nonaugmented bone sites and prosthetically treated with single crowns. All patients were examined during a 3- to 6-month recall schedule over a 10- to 20-year period, and clinical and radiographic examinations were performed. GBR yielded mean vertical and lateral bone gains of 4.5 and 7.0 mm, respectively. The implant survival rate was 100%, mucositis was present in 28.8% of sites, and peri-implantitis was not found. The annual bone loss at tooth sites was significantly higher than at implant sites in augmented bone (0.5% vs 0.2%, respectively; P = .000), and the adjacent teeth had significantly higher annual bone loss (0.8%; P = .000). Thus, severely periodontally compromised patients can be managed successfully in the long-term with the described clinical protocol.
摘要：
本病例系列的目的是评估在引导骨再生（GBR）后插入骨中的植入物。该研究招募了14例广泛性侵袭性牙周炎（GAP）患者，这些患者在切牙或前磨牙区域失去了一个或两个上颌牙齿。由于骨吸收，骨的横向宽度和垂直高度不足以放置植入物。使用钛增强的e-PTFE（膨胀聚四氟乙烯）膜以分阶段的方法进行GBR。没有使用骨移植物或骨替代材料。6到8个月后，将翻转表面植入物（n=47）插入增强和非增强的骨部位，并用单冠进行修复。所有患者在10至20年的3至6个月的召回计划中进行了检查，并进行了临床和影像学检查。GBR产生了4.5和7.0mm的平均垂直和外侧骨增益，分别。种植体成活率为100%,28.8%的部位存在粘膜炎，未发现种植体周围炎。牙齿部位的年度骨丢失显着高于增强骨的植入部位（0.5％vs0.2％，分别；P=.000)，相邻牙齿的年骨损失显着增加（0.8％；P=.000）。因此，严重牙周受损的患者可以通过所述临床方案在长期内得到成功治疗.
