PDF(Pubmed)
Abstract：
Endoscopic endonasal surgery has been demonstrated to be effective in the treatment of selected cases of sinonasal cancers. However, in cases of locally advanced neoplasms, as well as recurrences, the most appropriate approach is still debated. The present review aims to summarize the current state of knowledge on the utility of open approaches to resect sinonasal malignant tumours. Published comparative studies and meta-analyses suggest comparable oncological results with lower morbidity for the endoscopic approaches, but selection biases cannot be excluded. After a critical analysis of the available literature, it can be concluded that endoscopic surgery for selected lesions allows for oncologically safe resections with decreased morbidity. However, when endoscopic endonasal surgery is contraindicated and definitive chemoradiotherapy is not appropriate, craniofacial and transfacial approaches remain the best therapeutic option.
摘要：
鼻内镜手术已被证明可有效治疗选定的鼻窦癌病例。然而,在局部晚期肿瘤的情况下，以及复发，最合适的方法仍在争论中。本综述旨在总结有关开放方法切除鼻窦恶性肿瘤的实用性的知识现状。已发表的比较研究和荟萃分析表明，内镜方法的肿瘤学结果具有可比性，发病率较低。但不能排除选择偏差。在对现有文献进行批判性分析后，可以得出结论，对选定的病变进行内镜手术可以进行肿瘤学安全的切除，降低发病率。然而,当内镜鼻内手术是禁忌的，明确的放化疗是不合适的，颅面和经面入路仍然是最佳的治疗选择。
