关键词: acute pain dexketoprofen drugs in fixed-dose combinations (fdc) low-back pain (lbp) multimodal analgesia pain chronification tramadol acute pain dexketoprofen drugs in fixed-dose combinations (fdc) low-back pain (lbp) multimodal analgesia pain chronification tramadol

来  源:   DOI:10.7759/cureus.22465   PDF(Pubmed)

Abstract:
It is crucial that acute pain be promptly and adequately treated in order to prevent it from transitioning to chronic pain, a devastating and sometimes permanent condition that is challenging to treat and associated with disability, reduced quality of life, and depression. Guidelines for the treatment of acute low-back pain (LBP) are predicated on assumptions that all acute LBP is benign, temporary, and traditionally treated with a \"wait and see\" approach. LBP is far from a monolithic condition: etiology, the presence of underlying conditions, mental health status, social situation, patient\'s age and occupation, and comorbidities all present different risk factors for chronic LBP that should be considered in treating acute LBP or other forms of acute pain. A multimodal approach to acute pain has been shown to be safe and effective. In particular, the combination product of oral dexketoprofen and tramadol has been shown effective in controlling acute pain, which spares the use of opioids and is well tolerated. Chronic pain must be viewed as a global health crisis, and the timely and adequate control of acute painful conditions is a good strategy to reduce its prevalence. Experts at Roma Pain Days discussed this important topic which is the foundation of this review.
摘要:
重要的是要及时和充分治疗急性疼痛,以防止其转变为慢性疼痛。一种毁灭性的,有时是永久性的疾病,治疗具有挑战性,并与残疾有关,生活质量下降,和抑郁症。急性下腰痛(LBP)的治疗指南基于所有急性LBP均为良性的假设,temporary,传统上采用“观望”的方法。LBP远非单一疾病:病因,潜在条件的存在,心理健康状况,社会状况,患者的年龄和职业,和合并症均呈现不同的慢性LBP危险因素,在治疗急性LBP或其他形式的急性疼痛时应考虑这些危险因素.急性疼痛的多模式方法已被证明是安全有效的。特别是,口服右酮洛芬和曲马多的组合产品已被证明可有效控制急性疼痛,避免使用阿片类药物,并且耐受性良好。慢性疼痛必须被视为全球健康危机。及时和充分控制急性疼痛状况是降低其患病率的好策略。罗马疼痛日的专家讨论了这一重要主题,这是本评论的基础。
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