To review all existing literature on the systemic therapy of NXG in order to identify the most effective therapies.
All reported papers in the literature were screened for systemic treatments of NXG. Papers without proper description of the therapies, papers describing topical therapy, and articles without assessment of effectiveness were excluded. Subsequently, we analyzed 79 papers and a total of 175 cases.
The most effective treatments for NXG are intravenous immunoglobulins (IVIG), corticosteroids, and combination therapies including corticosteroids.
Corticosteroids and IVIG should therefore be considered first-line treatments in patients with NXG.
回顾所有关于NXG全身治疗的现有文献,以确定最有效的治疗方法。
文献中所有报道的论文均筛选了NXG的全身治疗。没有适当描述疗法的论文,描述局部治疗的论文,未评估有效性的文章被排除.随后,我们分析了79篇论文,共175例。
NXG最有效的治疗方法是静脉注射免疫球蛋白(IVIG),皮质类固醇,以及包括皮质类固醇在内的联合疗法。
因此,糖皮质激素和IVIG应被视为NXG患者的一线治疗。