Abstract：
BACKGROUND: The synchronous development of a medullary and papillary carcinoma as two different tumors has only been reported very rarely. The aim of the current report is to describe an extremely rare occurrence of medullary carcinoma, papillary microcarcinoma, and Hashimoto thyroiditis.
METHODS: A 53-year-old man presented with a right-sided neck mass. Ultrasound showed a well-defined nodule in the right mid third with microcalcification and increased nodular vascularity associated with multiple right-sided cervical lymphadenopathy. The histopathological examination showed multifocal medullary carcinoma with incidental finding of unifocal papillary microcarcinoma conventional type on the left side. Additional pathology of Hashimoto thyroiditis with a small intra-thyroidal parathyroid gland in the left thyroid gland. The procedure went perfectly and the patient was discharged home without any difficulties.
CONCLUSIONS: Synchronous existence of these two neoplasms can occur in two forms: distinct medullary carcinoma and papillary carcinoma isolated by normal thyroid tissue, or mixed medullary and follicular-derived thyroid carcinoma, in which single or multiple lesions show morphology and immunoreactivity for both medullary carcinoma and follicular-derived carcinoma.
CONCLUSIONS: The synchronous coexistence of papillary microcarcinoma, medullary carcinoma, and Hashimoto\'s thyroiditis is an uncommon thyroid condition.
METHODS: A 53-year-old man presented with a right-sided neck mass. Ultrasound showed a well-defined nodule in the right mid third with microcalcification and increased nodular vascularity associated with multiple right-sided cervical lymphadenopathy. The histopathological examination showed multifocal medullary carcinoma with incidental finding of unifocal papillary microcarcinoma conventional type on the left side. Additional pathology of Hashimoto thyroiditis with a small intra-thyroidal parathyroid gland in the left thyroid gland. The procedure went perfectly and the patient was discharged home without any difficulties.
CONCLUSIONS: Synchronous existence of these two neoplasms can occur in two forms: distinct medullary carcinoma and papillary carcinoma isolated by normal thyroid tissue, or mixed medullary and follicular-derived thyroid carcinoma, in which single or multiple lesions show morphology and immunoreactivity for both medullary carcinoma and follicular-derived carcinoma.
CONCLUSIONS: The synchronous coexistence of papillary microcarcinoma, medullary carcinoma, and Hashimoto\'s thyroiditis is an uncommon thyroid condition.
摘要：
背景：髓样和乳头状癌作为两种不同的肿瘤同步发展的报道很少。本报告的目的是描述一种极为罕见的髓样癌，乳头状微小癌，还有桥本甲状腺炎.
方法：一名53岁男子出现右侧颈部肿块。超声检查显示右侧中部有明确的结节，伴有微钙化和与多个右侧颈部淋巴结肿大相关的结节状血管增加。组织病理学检查显示多灶性髓样癌，左侧偶然发现单灶性乳头状微癌常规型。桥本甲状腺炎的其他病理，左侧甲状腺中的甲状腺甲状旁腺小。手术进行得很顺利，病人出院了，没有任何困难。
结论：这两种肿瘤可以两种形式同时存在：不同的髓样癌和正常甲状腺组织分离的乳头状癌，或者混合髓样和滤泡源性甲状腺癌，其中单个或多个病变显示髓样癌和滤泡源性癌的形态和免疫反应性。
结论：乳头状微小癌同步共存，髓样癌,桥本甲状腺炎是一种罕见的甲状腺疾病。
方法：一名53岁男子出现右侧颈部肿块。超声检查显示右侧中部有明确的结节，伴有微钙化和与多个右侧颈部淋巴结肿大相关的结节状血管增加。组织病理学检查显示多灶性髓样癌，左侧偶然发现单灶性乳头状微癌常规型。桥本甲状腺炎的其他病理，左侧甲状腺中的甲状腺甲状旁腺小。手术进行得很顺利，病人出院了，没有任何困难。
结论：这两种肿瘤可以两种形式同时存在：不同的髓样癌和正常甲状腺组织分离的乳头状癌，或者混合髓样和滤泡源性甲状腺癌，其中单个或多个病变显示髓样癌和滤泡源性癌的形态和免疫反应性。
结论：乳头状微小癌同步共存，髓样癌,桥本甲状腺炎是一种罕见的甲状腺疾病。
