关键词: Saliva cohort studies growth/development microbiota plaque/plaque biofilms

来  源:   DOI:10.1080/20002297.2022.2051352   PDF(Pubmed)

Abstract:
UNASSIGNED: Oral microbiota that established in the early years of life may influence the child\'s oral health in the long term. Until now, no consensus is reached about whether the development of the oral microbiota is more related with age increase or more with teeth eruption.
UNASSIGNED: To analyze the microbiota development of both saliva and supragingival plaque during the gradual eruption of primary teeth in caries-free infants and toddlers.
UNASSIGNED: Saliva and plaque samples were collected at five and four dentition states, respectively, and were identified by bacterial 16S rRNA gene sequencing.
UNASSIGNED: During the longitudinal observation, the saliva ecosystem seemed more complex and dynamic than the plaque, with larger bacteria quantity and more significantly varied species over time. About 70% of the initial colonized OTUs in plaque persisted until the completion of the primary dentition. Transient bacteria were mostly detected in the early saliva and plaque microbiota, which came from the environment and other sites of the human body. Microbial diversity in both saliva and plaque varied greatly from pre-dentition to full eruption of eight anterior teeth, but not during the eruption of primary molars.
UNASSIGNED: Oral bacterial development follows an ordered sequence during the primary teeth eruption. \'Fully eruption of all primary anterior teeth\' is a critical stage in this process.
摘要:
未经证实:生命早期建立的口腔微生物群可能会长期影响儿童的口腔健康。直到现在,关于口腔微生物群的发展是否与年龄增长更相关或与牙齿萌出更多相关,尚未达成共识。
UNASSIGNED:分析无龋婴幼儿乳牙逐渐萌出过程中唾液和牙龈上菌斑的微生物群发育。
未经评估:在五个和四个牙列状态下收集唾液和牙菌斑样本,分别,并通过细菌16SrRNA基因测序鉴定。
UNASSIGNED:在纵向观察期间,唾液生态系统似乎比斑块更复杂和动态,随着时间的推移,细菌数量更大,物种变化更显著。斑块中约有70%的初始定殖OTU持续存在,直到完成原牙列。瞬时细菌主要在早期唾液和斑块微生物群中检测到,来自环境和人体的其他部位。从牙列前到八颗前牙完全萌出,唾液和牙菌斑中的微生物多样性差异很大,但不是在原发性磨牙喷发期间。
未经证实:在乳牙萌出期间,口腔细菌发育遵循有序的顺序。“所有乳前牙完全萌出”是这一过程中的一个关键阶段。
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