PDF(Pubmed)
Abstract：
Pediatric-type follicular lymphoma is a disease that affects the lymph nodes of the head and neck in the adult and pediatric patient groups. Ocular involvement is exceedingly rare, especially in the pediatrics age group; therefore, keeping a high clinical suspicion is warranted. Here, we report a rare conjunctival pediatric-type follicular lymphoma in a 15-year-old boy presenting with progressive swelling over the medial aspect of the left bulbar conjunctiva for two months. On examination, the mass was firm, mobile, well encapsulated, wide-based, and had a negative transillumination. An excisional biopsy was performed, and histopathological examination and immunohistochemistry studies revealed lymphoid tissue that was positive for CD20, CD79a, BCL6, and CD10; and negative for BCL2 and MUM1. The CD21 and CD23 positivity highlighted the presence of an expanded follicular dendritic cell meshwork. The patient was diagnosed with conjunctival pediatric-type follicular lymphoma and referred to an oncology center for further examination and treatment. This lymphoma is rare, requiring high clinical suspicion, and thus, reporting the case detail is important and valuable for ophthalmologists and general pediatrics practitioners alike.
摘要：
小儿型滤泡性淋巴瘤是一种影响成人和小儿患者组的头颈部淋巴结的疾病。眼部受累非常罕见，特别是在儿科年龄组；因此，保持高度的临床怀疑是必要的。这里,我们报道了一例15岁男孩的罕见结膜小儿型滤泡性淋巴瘤,表现为左球结膜内侧进行性肿胀2个月.在检查中，质量是坚定的，mobile,封装良好，广泛的基础，并有一个负面的过渡。进行了切除活检，组织病理学检查和免疫组织化学研究显示淋巴组织CD20、CD79a阳性，BCL6和CD10;并且对BCL2和MUM1阴性。CD21和CD23阳性突出显示存在扩大的滤泡树突状细胞网。该患者被诊断为结膜小儿型滤泡性淋巴瘤，并转诊至肿瘤中心进行进一步检查和治疗。这种淋巴瘤很罕见,需要高度的临床怀疑，因此，报告病例细节对于眼科医生和普通儿科从业者都很重要和有价值。
