PDF(Pubmed)
Abstract：
The invasion of trophoblasts into the uterine decidua and decidual vessels is critical for the formation of placenta. The defects of placentation are related to the etiologies of preeclampsia (PE), fetal growth restriction (FGR), and small-for-gestational age (SGA) neonates. It is possible to predict significant vascular events during pregnancy through uterine artery Doppler (UAD). From the implantation stage to the end of pregnancy, detecting changes in uterine and placental blood vessels can provide a favorable diagnostic instrument for pregnancy complications. This review aims to collect literature about the roles of UAD in pregnancy complications. We consider all relevant articles in English from January 1, 1983 to October 30, 2021. Predicting pregnancy complications in advance allows practitioners to carry out timely interventions to avoid or lessen the harm to mothers and neonates. Administering low-dose aspirin daily before 16 weeks of pregnancy can significantly reduce the incidence of pregnancy complications. From early pregnancy to late pregnancy, UAD can combine with other maternal factors, biochemical indicators, and fetal measurement data to identify high-risk population. The identification of high-risk groups can also lessen maternal mortality. Besides, through moderate risk stratification, stringent monitoring for high-risk pregnant women can be implemented, decreasing the incidence of adversities.
摘要：
滋养细胞侵入子宫蜕膜和蜕膜血管对胎盘形成至关重要。胎盘形成的缺陷与子痫前期（PE）的病因有关，胎儿生长受限（FGR），和小于胎龄儿（SGA）的新生儿。通过子宫动脉多普勒（UAD）可以预测妊娠期间的重大血管事件。从植入阶段到妊娠结束，检测子宫和胎盘血管的变化可以为妊娠并发症提供有利的诊断手段。本综述旨在收集有关UAD在妊娠并发症中的作用的文献。我们考虑从1983年1月1日到2021年10月30日的所有相关英文文章。提前预测妊娠并发症可以使医生及时进行干预，以避免或减轻对母亲和新生儿的伤害。妊娠16周前每日服用小剂量阿司匹林可显著降低妊娠并发症的发生率。从妊娠早期到妊娠晚期，UAD可以与其他母体因素相结合，生化指标,和胎儿测量数据来识别高危人群。确定高危人群也可以降低孕产妇死亡率。此外,通过适度的风险分层，可以对高风险孕妇实施严格的监测，降低逆境的发生率。
