PDF(Pubmed)
Abstract：
Pyoderma gangrenosum is a rare, chronic neutrophilic dermatosis of unknown etiology. The classical clinical feature of pyoderma gangrenosum is a pustule or plaque that rapidly progresses to a painful, necrotic ulcer with undermined violaceous margins. Pyoderma gangrenosum may be associated with underlying inflammatory bowel diseases, hematological malignancies, or rheumatologic disorders in 50-70% of the cases. The visceral involvement by pyoderma gangrenosum is rare. Sterile neutrophilic infiltrates in organs other than the skin are uncommon systemic manifestations of neutrophilic dermatoses, but have occasionally been reported. We report a case of a 38-year-old female with pyoderma gangrenosum and visceral involvement manifesting as splenic abscess.
摘要：
坏疽性脓皮病是一种罕见的，病因不明的慢性中性粒细胞性皮肤病。坏疽性脓皮病的经典临床特征是脓疱或斑块迅速发展为疼痛，坏死性溃疡，裂隙边缘。坏疽性脓皮病可能与潜在的炎症性肠病有关，血液恶性肿瘤，或风湿性疾病在50-70％的病例。坏疽性脓皮病的内脏受累很少。除皮肤以外的器官中的无菌嗜中性粒细胞浸润是嗜中性皮肤病的罕见全身表现，但偶尔有报道。我们报告了一例38岁的女性，患有坏疽性脓皮病和内脏受累，表现为脾脓肿。
