Abstract:
A 64-year-old female with complaints of swelling right preauricular region was referred to our tertiary cancer center with fine-needle aspiration cytology (FNAC) report of mucoepidermoid carcinoma and radiological differential of malignant salivary gland neoplasm and sarcoma. On examination, there was a mass over her right parotid region Clinical diagnosis was malignant salivary gland neoplasm. Slide review of FNAC was inconclusive. Biopsy was done. Histopathology showed neoplasm comprising of nests of cells with abundant granular eosinophilic cytoplasm with focal area showing peripherally arranged columnar cells with palisading. On enquiry, the patient gave a history of surgery of right mandible 48 years back. Correlating histopathology and clinical history, a diagnosis of granular cell ameloblastoma was rendered. Radiological evaluation showed a solid-cystic lesion in the right masticator space. Right mandible showed only part of head of mandible consistent with previous surgery. Radical surgery was done. Final report confirmed the biopsy diagnosis.
摘要:
一名64岁的女性主诉右耳前区域肿胀,被转诊到我们的三级癌症中心,并进行了细针穿刺细胞学检查(FNAC),报告了粘液表皮样癌以及恶性唾液腺肿瘤和肉瘤的放射学差异。在检查中,她的右腮腺区域有一个肿块。临床诊断为恶性涎腺肿瘤。FNAC的幻灯片审查没有定论。活检已完成。组织病理学显示肿瘤由具有丰富的颗粒状嗜酸性细胞浆的细胞巢组成,局灶性区域显示外围排列的柱状细胞,并带有栅栏。经询问,患者有48年的右下颌骨手术史。相关组织病理学和临床病史,诊断为颗粒细胞成釉细胞瘤。放射学评估显示右咀嚼器腔有实囊性病变。右下颌骨仅显示部分与先前手术一致的下颌骨头部。进行了根治性手术。最终报告证实活检诊断。