Abstract：
OBJECTIVE: To report the effectiveness of the surgical procedure of the tarsoconjunctival flap (FTC) in patients with severe ocular surface impairment refractory to previous conventional treatments.
METHODS: A retrospective, noncomparative, consecutive case series.
RESULTS: Pillar tarsoconjunctival flap (PTCF) was performed in eight eyes of eight patients. Three patients had neurotrophic corneal ulcer (NCU), three had exposure keratopathy and two had corneal melting. Seven of them had satisfactory postoperative results, showing total corneal re-epithelialization that lasted throughout the postoperative follow-up (mean 10.33 ± 2.65 months [SD], range 6 to 12 months). Mean time for the re-epithelization was 11.28 ± 8.97 days [SD] (range 4 to 30 days).
CONCLUSIONS: This study suggest PTCF is a valid alternative to tarsorrhaphy in cases of persistent epithelial defect (PED) or NCU resistant to conventional treatments. Notwithstanding, prospective comparative trials comparing PTFC with conventional and/or novel therapies in PED or NCU are needed to corroborate these findings.
METHODS: A retrospective, noncomparative, consecutive case series.
RESULTS: Pillar tarsoconjunctival flap (PTCF) was performed in eight eyes of eight patients. Three patients had neurotrophic corneal ulcer (NCU), three had exposure keratopathy and two had corneal melting. Seven of them had satisfactory postoperative results, showing total corneal re-epithelialization that lasted throughout the postoperative follow-up (mean 10.33 ± 2.65 months [SD], range 6 to 12 months). Mean time for the re-epithelization was 11.28 ± 8.97 days [SD] (range 4 to 30 days).
CONCLUSIONS: This study suggest PTCF is a valid alternative to tarsorrhaphy in cases of persistent epithelial defect (PED) or NCU resistant to conventional treatments. Notwithstanding, prospective comparative trials comparing PTFC with conventional and/or novel therapies in PED or NCU are needed to corroborate these findings.
摘要：
目的：报告对既往常规治疗难以治疗的严重眼表损伤患者，采用骨结膜瓣（FTC）手术治疗的有效性。
方法：回顾性研究，非比较性，连续病例系列。
结果：在8例患者的8只眼中进行了柱板结膜瓣（PTCF）。3例患者患有神经营养性角膜溃疡（NCU），3例发生暴露性角膜病变,2例发生角膜融化.其中7例术后效果满意,显示整个术后随访期间的全角膜上皮再形成(平均10.33±2.65个月[SD],6至12个月)。上皮再形成的平均时间为11.28±8.97天[SD]（范围为4至30天）。
结论：这项研究表明，在持续性上皮缺损（PED）或NCU对常规治疗耐药的情况下，PTCF是一种有效的替代方法。尽管如此,需要将PTFC与PED或NCU中的常规和/或新疗法进行比较的前瞻性比较试验来证实这些发现。
方法：回顾性研究，非比较性，连续病例系列。
结果：在8例患者的8只眼中进行了柱板结膜瓣（PTCF）。3例患者患有神经营养性角膜溃疡（NCU），3例发生暴露性角膜病变,2例发生角膜融化.其中7例术后效果满意,显示整个术后随访期间的全角膜上皮再形成(平均10.33±2.65个月[SD],6至12个月)。上皮再形成的平均时间为11.28±8.97天[SD]（范围为4至30天）。
结论：这项研究表明，在持续性上皮缺损（PED）或NCU对常规治疗耐药的情况下，PTCF是一种有效的替代方法。尽管如此,需要将PTFC与PED或NCU中的常规和/或新疗法进行比较的前瞻性比较试验来证实这些发现。
