PDF(Pubmed)
Abstract：
Nocardiosis is a rare opportunistic gram-positive bacterial infection. The genus Nocardia consists of non-motile, aerobic, non-spore-forming, catalase-positive, filamentous-branching bacteria with fragmentation into coccoid or bacillary forms. Opportunistic infections due to Nocardia are reported in immunocompromised patients. Aspergillus fumigatus is a conidia forming fungus that can be found in soil, plant matter and dust, causing invasive pulmonary and disseminated infection in immunocompromised patients. Both Nocardia cyriacigeorgica and A. fumigatus are known to cause pulmonary infection with metastatic dissemination to the central nervous system. We present a case of Nocardia and Aspergillus co-infection in a patient who presented within a few days of initiation of immunosuppressants for suspected systemic lupus erythematosus.
摘要：
诺卡病是一种罕见的机会性革兰氏阳性细菌感染。诺卡氏菌属由不运动的，有氧,非孢子形成，过氧化氢酶阳性,丝状分支细菌，分裂成球形或杆菌形式。据报道，在免疫功能低下的患者中，诺卡氏菌引起的机会性感染。烟曲霉是一种分生孢子形成真菌，可以在土壤中发现，植物物质和灰尘，在免疫功能低下的患者中引起侵袭性肺部和播散性感染。已知白囊诺卡氏菌和烟曲霉都会引起肺部感染，并转移到中枢神经系统。我们介绍了一例诺卡氏菌和曲霉共感染的患者，该患者在疑似系统性红斑狼疮开始使用免疫抑制剂后几天内出现。
