Abstract：
BACKGROUND: Head and neck photoimmunotherapy specifically destroys tumor cells by irradiating them with 690 nm red light after administering cetuximab sarotalocan sodium. The key point in the technique of photoimmunotherapy is to set the irradiation area precisely with a margin added to the target lesion while securing a safety zone with large vessels such as the internal carotid artery.
METHODS: At our Institution, we performed photoimmunotherapy in combination with use of a navigation system on a male patient in his 70s with maxillary gingival carcinoma who had a recurrent lesion deep in the lateral pterygoid muscle. Three months after photoimmunotherapy, the superficial lesion had disappeared, the area of contrast within the lateral pterygoid muscle had improved, and the patient was deemed to have a complete response.
CONCLUSIONS: The Navigation System was successfully used in combination with photoimmunotherapy. Additionally, this allowed the location of the internal carotid artery to be confirmed in real time.
METHODS: At our Institution, we performed photoimmunotherapy in combination with use of a navigation system on a male patient in his 70s with maxillary gingival carcinoma who had a recurrent lesion deep in the lateral pterygoid muscle. Three months after photoimmunotherapy, the superficial lesion had disappeared, the area of contrast within the lateral pterygoid muscle had improved, and the patient was deemed to have a complete response.
CONCLUSIONS: The Navigation System was successfully used in combination with photoimmunotherapy. Additionally, this allowed the location of the internal carotid artery to be confirmed in real time.
摘要：
背景：头颈部光免疫疗法通过在施用西妥昔单抗沙洛酮醇钠后用690nm红光照射肿瘤细胞来特异性地破坏肿瘤细胞。光免疫疗法技术的关键点是精确地设置照射区域，并在目标病变上增加边缘，同时确保具有大血管（例如颈内动脉）的安全区。
方法：在我们的机构，我们对一名70多岁患有上颌牙龈癌的男性患者进行了光免疫疗法，该患者在翼外肌深处有复发性病变。光免疫疗法三个月后，浅表病变消失了,翼外肌内的对比区域有所改善，患者被认为有完全反应。
结论：导航系统成功地与光免疫疗法结合使用。此外,这允许实时确认颈内动脉的位置。
方法：在我们的机构，我们对一名70多岁患有上颌牙龈癌的男性患者进行了光免疫疗法，该患者在翼外肌深处有复发性病变。光免疫疗法三个月后，浅表病变消失了,翼外肌内的对比区域有所改善，患者被认为有完全反应。
结论：导航系统成功地与光免疫疗法结合使用。此外,这允许实时确认颈内动脉的位置。
