PDF(Pubmed)
Abstract：
Eosinophilic esophagitis is a chronic, immune-mediated esophageal condition that may lead to impairment of quality of life in pediatric and young adult patients. We performed a prospective, cross-sectional study on 40 patients between the ages of 2-21 years with an established diagnosis of eosinophilic esophagitis. The study evaluated physical, emotional, social, and school functioning in patients undergoing treatment with proton pump inhibitors, dietary elimination, or swallowed corticosteroids. There were no statistically significant differences in total or domain-specific quality of life scores between proton pump inhibitors, dietary elimination, and swallowed corticosteroid therapy. Overall, total and domain-specific quality of life were well-preserved in patients with eosinophilic esophagitis, with the highest scores reported in social functioning. There were also no statistically significant associations between clinical, endoscopic, and histologic features and quality-of-life measures.
摘要：
嗜酸细胞性食管炎是一种慢性,免疫介导的食管疾病可能导致儿童和年轻成人患者的生活质量受损。我们做了一个潜在的，对40例2-21岁确诊为嗜酸性粒细胞性食管炎患者的横断面研究。这项研究评估了身体，情感,社会,和接受质子泵抑制剂治疗的患者的学校功能，饮食消除，或者吞下皮质类固醇.质子泵抑制剂之间的总生活质量评分或特定领域生活质量评分无统计学差异，饮食消除，和吞咽皮质类固醇治疗。总的来说,嗜酸细胞性食管炎患者的总生活质量和特定领域生活质量得到了很好的保持，社会功能得分最高。临床，内窥镜,组织学特征和生活质量指标。
