关键词: Brain white matter injury Cardiovascular risk Htlv-1-associated myelopathy Magnetic resonance imaging Tropical spastic paraparesis

Mesh : Aged Brain / diagnostic imaging pathology Cardiovascular Diseases Female Heart Disease Risk Factors Human T-lymphotropic virus 1 Humans Male Middle Aged Nervous System Diseases Paraparesis, Tropical Spastic / pathology Risk Factors White Matter / diagnostic imaging pathology

来  源:   DOI:10.1007/s13365-022-01063-6

Abstract:
The origin of brain white matter lesion found in HTLV-1-associated myelopathy (HAM/TSP) remains undefined. We investigated the association between white matter lesions in HAM/TSP with cardiovascular risk factors. The group of 40 patients with HAM/TSP included 60% females and mean age of 58.6 ± 8 years old. The probability of 10-year cardiovascular disease was low in 53%, moderate in 38%, and high in 10% of the patients. There was no difference between the cardiovascular risk factors in HAM/TSP patients with and without brain lesions (p > 0.05). Our data suggest that the brain white matter abnormalities are not associated to increased cardiovascular risk in HAM/TSP.
摘要:
在HTLV-1相关脊髓病(HAM/TSP)中发现的脑白质病变的起源仍未定义。我们调查了HAM/TSP中白质病变与心血管危险因素之间的关系。40例HAM/TSP患者包括60%的女性,平均年龄为58.6±8岁。10年心血管疾病的可能性很低,为53%,中等在38%,在10%的患者中很高。HAM/TSP患者有无脑损害的心血管危险因素之间无差异(p>0.05)。我们的数据表明,脑白质异常与HAM/TSP的心血管风险增加无关。
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