关键词: healthcare-associated infections hemodialysis outbreaks waterborne infections healthcare-associated infections hemodialysis outbreaks waterborne infections

来  源:   DOI:10.1093/ofid/ofac058   PDF(Pubmed)

Abstract:
Individuals treated with dialysis are at high risk for healthcare-associated infections. We conducted a literature review of outbreaks associated with water in hemodialysis during years 2011-2021 to understand the role of water as a source of infections for patients receiving hemodialysis with a focus on the risks associated with dialysis water and dialysate. For dialysis patients, water and dialysate have been a source of healthcare-associated pathogens, including nontuberculous mycobacteria and gram-negative bacilli as well as systemic reactions due to gram-negative bacilli-associated endotoxin. Lapses in infection prevention practices and dialysis water management were primarily involved in waterborne outbreaks. Dialysis clinics should adhere to recommendations regarding monitoring and levels of bacteria and endotoxin in hemodialysis water and dialysate. Since hemodialysis patients are at increased risk of healthcare-associated infections, it is important for healthcare personnel to adhere to infection prevention guidelines in hemodialysis patient care, especially hand hygiene, aseptic technique, cleaning/disinfection, and water management.
摘要:
接受透析治疗的个体面临医疗保健相关感染的高风险。我们对2011-2021年期间血液透析中与水相关的爆发进行了文献综述,以了解水作为血液透析患者感染源的作用,重点关注与透析水和透析液相关的风险。对于透析患者,水和透析液一直是医疗保健相关病原体的来源,包括非结核性分枝杆菌和革兰氏阴性杆菌以及革兰氏阴性杆菌相关内毒素引起的全身反应。感染预防措施和透析水管理的失败主要涉及水传播的暴发。透析诊所应遵守有关监测血液透析水和透析液中细菌和内毒素水平的建议。由于血液透析患者的医疗保健相关感染风险增加,对于医护人员来说,在血液透析患者护理中遵守感染预防指南非常重要,尤其是手部卫生,无菌技术,清洁/消毒,和水管理。
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