Abstract：
Healthcare professionals require effective treatment options for managing the complications that may arise during cancer treatment. The Multinational Association of Supportive Care in Cancer (MASCC) and the International Society of Oral Oncology (ISOO) work together to reduce oral complications secondary to cancer, including difficulties associated with oral mucositis (OM). The present article is intended to summarize the MASCC/ISOO guidelines, which are updated periodically based on the most recent evidence supporting the multiple treatment options for OM caused by chemotherapy and radiotherapy used to treat head and neck tumors. The Mucositis Study Group (MSG) of MASCC/ ISOO conducted systematic reviews of the current literature pertaining to several interventions, including anti-inflammatory agents; basic oral care; vitamins, minerals, and nutritional supplements; and photobiomodulation. The MSG then categorized the effectiveness of each treatment for preventing OM or reducing the severity, duration, and reported pain of patients with OM based on the type of cancer being treated, the cancer treatment modality (chemotherapy, radiotherapy, or combination therapy), and the goals of the OM treatment (preventive or therapeutic). The present article also describes a case demonstrating the positive effects of using various laser devices to heal the symptoms of OM in a patient undergoing radiotherapy and chemotherapy for a squamous cell carcinoma at the base of the tongue.
摘要：
医疗保健专业人员需要有效的治疗方案来管理癌症治疗期间可能出现的并发症。跨国癌症支持护理协会（MASCC）和国际口腔肿瘤学会（ISOO）共同努力，减少继发于癌症的口腔并发症，包括与口腔粘膜炎（OM）相关的困难。本文旨在总结MASCC/ISOO指南，根据支持由用于治疗头颈部肿瘤的化疗和放疗引起的OM的多种治疗选择的最新证据，定期更新。MASCC/ISOO的粘膜炎研究组（MSG）对与几种干预措施有关的现有文献进行了系统回顾，包括抗炎药；基本口腔护理；维生素，矿物,和营养补充剂；和光生物调节。然后，MSG对每种治疗方法的有效性进行分类，以预防OM或降低严重程度，持续时间,并根据所治疗的癌症类型报告了OM患者的疼痛，癌症治疗方式(化疗，放射治疗,或联合治疗)，和OM治疗的目标（预防性或治疗性）。本文还描述了一个案例，该案例证明了使用各种激光设备来治愈正在接受放射疗法和化学疗法治疗舌根鳞状细胞癌的患者的OM症状的积极作用。
