关键词: electron beam gamma irradiation ionizing radiation killed vaccines vaccines

Mesh : Gamma Rays Radiation, Ionizing Technology Vaccine Development

来  源:   DOI:10.3389/fimmu.2022.845514   PDF(Pubmed)

Abstract:
Given the current pandemic the world is struggling with, there is an urgent need to continually improve vaccine technologies. Ionizing radiation technology has a long history in the development of vaccines, dating back to the mid-20th century. Ionizing radiation technology is a highly versatile technology that has a variety of commercial applications around the world. This brief review summarizes the core technology, the overall effects of ionizing radiation on bacterial cells and reviews vaccine development efforts using ionizing technologies, namely gamma radiation, electron beam, and X-rays.
摘要:
鉴于当前世界正在努力应对的流行病,迫切需要不断改进疫苗技术。电离辐射技术在疫苗开发中有着悠久的历史,可以追溯到20世纪中叶。电离辐射技术是一种高度通用的技术,在世界各地具有多种商业应用。这篇简短的综述总结了核心技术,电离辐射对细菌细胞的总体影响,并回顾了使用电离技术的疫苗开发工作,即伽马辐射,电子束,还有X光片.
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