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Abstract：
We experienced a rare case of severe peripheral ulcerative keratitis in a patient undergoing surgery combined with deep anterior lamellar keratoplasty (DALK) and peripheral lamellar keratoplasty (LK). A 63-year-old Japanese woman was referred to our hospital for the treatment of visual disturbance caused by peripheral ulcerative keratitis in the left eye. Although the inflammation subsided with topical and oral administration of steroids, peripheral ulcerative keratitis worsened 4 weeks after the medical treatment. Surgery combining DALK and peripheral LK, including the corneal limbus, was performed as treatment. Two weeks after the surgery, a double anterior chamber appeared, but it disappeared spontaneously. There was no postoperative rejection or intraocular pressure elevation. One year and 6 months after the surgery, the inflammation did not recur, the cornea remained transparent, and the thickness of the cornea was maintained. In conclusion, combined DALK and peripheral LK may be a surgical option for treating severe peripheral ulcerative keratitis.
摘要：
我们在接受手术联合深前板层角膜移植术（DALK）和周围板层角膜移植术（LK）的患者中经历了一例罕见的严重周围溃疡性角膜炎。一名63岁的日本妇女被转诊到我们医院治疗左眼周围溃疡性角膜炎引起的视觉障碍。尽管局部和口服类固醇可以缓解炎症，周围溃疡性角膜炎在药物治疗4周后恶化。手术结合DALK和外周LK，包括角膜缘,作为治疗进行。手术两周后,出现了双前房，但它自然消失了.术后无排斥反应或眼压升高。手术后一年零六个月，炎症没有复发,角膜保持透明,并保持角膜的厚度。总之,DALK和外周LK联合治疗可能是治疗严重外周溃疡性角膜炎的手术选择.
