Abstract：
(1) Background: This study aimed to analyze the impact of surgical approach on survival rates in women diagnosed with endometrial cancer. (2) Methods: A retrospective multicenter cohort of 1382 women diagnosed with EC was performed. A total of 684 (49.5%) women underwent minimally invasive surgery, 233 (34%) underwent robotic-assisted laparoscopy (RAL), 451 (66%) underwent conventional laparoscopy (LPS), and 698 (50.5%) underwent open surgery (OP). Sociodemographic features, tumor characteristics, and survival rates were analyzed in the whole sample and in a matched-pair model. (3) Results: Women operated on by OP were significantly older, presented more comorbidities, and had more aggressive tumors. Disease-free (DFS), overall (OS), and specific survival related to EC (SS) amounts were significantly higher for MIS compared to OP (p < 0.001). When matched by age, body mass index, comorbidities, ASA score, histological type, grade, myometrial invasion, and FIGO stage, 798 patients were selected. DFS, OS, and SS amounts were similar between the MIS and OP groups. (4) Conclusions: The surgical approach for women with EC does not impact DFS or OS amounts when matched by homogeneous groups.
摘要：
(1)背景：本研究旨在分析子宫内膜癌患者手术方式对生存率的影响。（2）方法：对1382例诊断为EC的妇女进行了回顾性多中心队列研究。共有684名(49.5%)女性接受了微创手术,233（34%）接受了机器人辅助腹腔镜检查（RAL），451（66％）接受了常规腹腔镜检查（LPS），698人（50.5%）接受了开放手术（OP）。社会人口学特征，肿瘤特征，在整个样本和配对模型中分析生存率。（3）结果：OP手术的妇女年龄明显较大，带来了更多的合并症，并且有更具侵袭性的肿瘤。无病（DFS），总体(OS)，与OP相比，MIS和与EC（SS）量相关的特异性生存率显着更高（p<0.001）。当按年龄匹配时，身体质量指数,合并症,ASA得分,组织学类型,grade,子宫肌层浸润，和FIGO阶段，选择798例患者。DFS,操作系统,MIS组和OP组的SS量相似。（4）结论：与同质组匹配时，女性EC的手术方法不会影响DFS或OS量。
