Abstract：
Cardiac Contractility Modulation (CCM) has been proposed for inpatients affected by heart failure with reduced ejection fraction (HFrEF), with relapsing HF symptoms. We present a case of a patient treated with percutaneous coronary intervention (PCI) in the setting of acute coronary syndrome without persistent ST-segment elevation, with the best medical therapy for decompensated HF. The patient refused the implantable cardioverter-defibrillator (ICD), and to reduce the increasing number of hospitalizations for HF exacerbations, we proposed the use of the cardiac contractility modulation device. After the implant, the patient demonstrated a marked improvement in exercise effort and quality of life (QOL) with a six-minute walk test (SMWT), Minnesota Living with Heart Failure Questionnaire (MLWHFQ), and echocardiographic parameters. At 9 months after discharge, no hospital admissions for HF were recorded. We showed with the speckle tracking imaging how the improvement in global longitudinal strain (GLS) correlates with the remodeling effects on myocardial cells.
摘要：
心脏收缩力调节（CCM）已被提议用于患有射血分数降低的心力衰竭（HFrEF）的住院患者。有复发性HF症状.我们介绍了一例在急性冠状动脉综合征的情况下接受经皮冠状动脉介入治疗（PCI）的患者，该患者没有持续的ST段抬高，用最好的药物治疗失代偿性HF。患者拒绝植入心脏复律除颤器(ICD),并减少因HF恶化而住院的人数增加，我们建议使用心脏收缩力调节装置。植入后,通过六分钟步行测试（SMWT），患者的运动努力和生活质量（QOL）显着改善，明尼苏达州心力衰竭生活问卷（MLWHFQ），和超声心动图参数。出院后9个月，没有因HF入院的记录.我们通过斑点追踪成像显示了整体纵向应变（GLS）的改善如何与对心肌细胞的重塑影响相关。
