PDF(Pubmed)
Abstract：
OBJECTIVE: To determine factors associated with repeat revascularization among adults aged 25 years and above within 5 years of first Percutaneous Coronary Intervention (PCI) at a tertiary care hospital.
METHODS: A matched case-control study was conducted through a hospital records review. A total of 90 cases with repeat revascularization and 180 controls without repeat revascularization were included. Data was analyzed using Multiple Conditional Logistic Regression.
RESULTS: The mean age was similar in cases and controls (60.05 ± 10.01 vs 62.20 ± 10.43 years) and sex (male: 77.8% vs. 76.1%). History of being an ever-smoker (40% vs. 25%), overweight (36.3% vs. 30.6%), and poor glycemic control (23.3% vs. 12.2%) were more among the cases than controls. However, obesity (53.7% vs. 44.3%) and pre-diabetes (16.1% vs. 7.8%) were more in controls compared to cases.Upon matching on the time of index PCI, the adjusted odds of ever smokers among patients with repeat revascularization was 2.47 times the odds of ever smokers among patients who did not undergo revascularization. Increasing stent diameter by 1 mm was found to reduce the risk of repeat revascularization by 51%.
CONCLUSIONS: Smoking cessation and appropriate selection of stent diameter in patients undergoing revascularization can reduce the risk of repeat revascularization in the future.
METHODS: A matched case-control study was conducted through a hospital records review. A total of 90 cases with repeat revascularization and 180 controls without repeat revascularization were included. Data was analyzed using Multiple Conditional Logistic Regression.
RESULTS: The mean age was similar in cases and controls (60.05 ± 10.01 vs 62.20 ± 10.43 years) and sex (male: 77.8% vs. 76.1%). History of being an ever-smoker (40% vs. 25%), overweight (36.3% vs. 30.6%), and poor glycemic control (23.3% vs. 12.2%) were more among the cases than controls. However, obesity (53.7% vs. 44.3%) and pre-diabetes (16.1% vs. 7.8%) were more in controls compared to cases.Upon matching on the time of index PCI, the adjusted odds of ever smokers among patients with repeat revascularization was 2.47 times the odds of ever smokers among patients who did not undergo revascularization. Increasing stent diameter by 1 mm was found to reduce the risk of repeat revascularization by 51%.
CONCLUSIONS: Smoking cessation and appropriate selection of stent diameter in patients undergoing revascularization can reduce the risk of repeat revascularization in the future.
摘要：
目的：确定三级医院首次经皮冠状动脉介入治疗（PCI）后5年内25岁及以上成人再次血运重建的相关因素。
方法：通过医院记录回顾进行匹配的病例对照研究。共包括90例重复血运重建和180例未重复血运重建的对照。使用多条件Logistic回归分析数据。
结果：病例和对照组的平均年龄相似（60.05±10.01vs62.20±10.43岁）和性别（男性：77.8％vs.76.1%）。成为吸烟者的历史（40％与25%），超重（36.3%vs.30.6%），血糖控制不佳(23.3%vs.12.2%)的病例比对照组多。然而,肥胖症（53.7%vs.44.3%）和糖尿病前期（16.1%vs.与病例相比，对照组为7.8％）。在与指数PCI时间匹配后，重复血运重建患者中曾经吸烟者的校正几率是未接受血运重建患者中曾经吸烟者的2.47倍。发现支架直径增加1mm可将重复血运重建的风险降低51％。
结论：在接受血运重建的患者中，戒烟和适当选择支架直径可以降低将来再次血运重建的风险。
方法：通过医院记录回顾进行匹配的病例对照研究。共包括90例重复血运重建和180例未重复血运重建的对照。使用多条件Logistic回归分析数据。
结果：病例和对照组的平均年龄相似（60.05±10.01vs62.20±10.43岁）和性别（男性：77.8％vs.76.1%）。成为吸烟者的历史（40％与25%），超重（36.3%vs.30.6%），血糖控制不佳(23.3%vs.12.2%)的病例比对照组多。然而,肥胖症（53.7%vs.44.3%）和糖尿病前期（16.1%vs.与病例相比，对照组为7.8％）。在与指数PCI时间匹配后，重复血运重建患者中曾经吸烟者的校正几率是未接受血运重建患者中曾经吸烟者的2.47倍。发现支架直径增加1mm可将重复血运重建的风险降低51％。
结论：在接受血运重建的患者中，戒烟和适当选择支架直径可以降低将来再次血运重建的风险。
