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Abstract：
Rheumatoid arthritis (RA) is an autoimmune disease characterized by erosive arthritis, which can involve multiple systems. Patients with RA may have a variety of comorbidities, including cardiovascular disease (CVD), lung cancer, lymphoma, infection, osteoporosis, fatigue, depression, colon cancer, breast cancer, prostate cancer, and Alzheimer\'s disease. Among these comorbidities, the incidence of CVD, lung cancer, lymphoma, infection, and osteoporosis is higher. CVD is a serious complication of RA. The risk of CVD and associated mortality rate in patients with RA is high, and the treatment rate is low. In addition to traditional risk factors, such as age, sex, blood pressure, and diabetes, RA is also associated with inflammation. Furthermore, therapeutic drugs for RA, including non-steroidal anti-inflammatory drugs, glucocorticoids, and disease-modifying anti-rheumatic drugs, have beneficial or harmful effects on cardiovascular events in patients with RA. This article discusses the effects of therapeutic drugs for RA on cardiovascular events.
摘要：
类风湿性关节炎（RA）是一种以糜烂性关节炎为特征的自身免疫性疾病，这可能涉及多个系统。RA患者可能有多种合并症，包括心血管疾病（CVD），肺癌,淋巴瘤感染,骨质疏松,疲劳,抑郁症,结肠癌,乳腺癌,前列腺癌,和老年痴呆症。在这些合并症中，CVD的发病率，肺癌,淋巴瘤感染,骨质疏松症更高。CVD是RA的严重并发症。RA患者的CVD风险和相关死亡率很高，且治疗率低。除了传统的风险因素，比如年龄,性别,血压,糖尿病,RA也与炎症相关。此外，治疗RA的药物，包括非甾体抗炎药,糖皮质激素,和改善疾病的抗风湿药，对RA患者的心血管事件有有益或有害的影响。本文讨论了RA治疗药物对心血管事件的影响。
