PDF(Pubmed)
Abstract：
Scleroderma is a family of systemic and local diseases that tighten and harden the skin and other connective tissues. Local scleroderma (i.e., morphea) typically involves the skin and underlying tissue causing progressive functional and cosmetic disturbances. While the etiology of scleroderma is unknown, it is correlated with autoimmune dysfunction. Linear morphea is a disorder that primarily affects children. This report describes the case of a nine-year-old girl with skin eruptions in the forehead, near the left eye, and in the anterior neck in addition to an underlying focal hemispheric frontal brain atrophy. There is no evidence of neurological deficits in this case. Linear morphea can lead to brain atrophy, causing several neurological dysfunctions such as seizures and cognitive impairment. Follow-up monitoring is critical, and also early recognition of new symptoms for optimal patient outcomes.
摘要：
硬皮病是全身和局部疾病的家族，会收紧和硬化皮肤和其他结缔组织。局部硬皮病(即，硬斑病）通常涉及皮肤和下层组织，引起进行性功能和美容障碍。虽然硬皮病的病因尚不清楚，它与自身免疫功能障碍有关。线性硬骨病是一种主要影响儿童的疾病。这份报告描述了一个9岁女孩的额头皮肤喷发的案例，靠近左眼，除了潜在的局灶性半球额叶脑萎缩之外，还有前颈部。在这种情况下没有神经缺陷的证据。线形硬伤会导致脑萎缩,引起几种神经系统功能障碍，如癫痫发作和认知障碍。后续监测至关重要,以及早期识别新症状以获得最佳患者预后。
