大蒜素改善肠上皮细胞屏障功能并防止 LPS 诱导的肠上皮细胞单层屏障损伤。
关键词: IPEC-J2 Nrf2 allicin intestinal barrier lipopolysaccharide oxidative damage
Mesh : Animals Cell Line Disulfides / pharmacology Electric Impedance Endoplasmic Reticulum Stress / drug effects Epithelial Cells / metabolism Heme Oxygenase-1 / metabolism Jejunum / drug effects metabolism physiology Lipopolysaccharides / toxicity NF-E2-Related Factor 2 / metabolism Permeability / drug effects Signal Transduction / drug effects Sulfinic Acids / pharmacology Swine Tight Junction Proteins / metabolism
来 源:
DOI:10.3389/fimmu.2022.847861
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