关键词: Geant4 ICRP InterDosi Nuclear medicine Phantom SAF

Mesh : Adult Female Humans Monte Carlo Method Nuclear Medicine Phantoms, Imaging Radiation Dosage Radiation Protection Radiometry / methods Radiotherapy Planning, Computer-Assisted Reference Values

来  源:   DOI:10.1016/j.apradiso.2022.110145

Abstract:
The International Commission on Radiological Protection (ICRP) through its publications recommends the estimation of Specific Absorbed Fractions (SAFs) using voxelized phantoms in order to assess the doses internally absorbed by organs exposed to ionizing radiation. In the present work, we report a large set of SAFs calculated using the ICRP Adult Female (ICRP-AF) phantom. The new Geant4-based code called InterDosi version 1.0 was used to simulate monoenergetic electrons of 20 different energies, ranging from 0.005 to 10 MeV, emitted uniformly from 18 different source organs. In order to estimate SAFs in 169 target organs/regions, 360 Monte Carlo multithreaded simulations were run on 32 CPUs of the HPC-MARWAN-CNRST computing grid. The calculated SAFs were compared to the recent results obtained using GATE 8.1 code and published by the OpenDose collaboration. It is shown that the obtained results are in well-agreement with the reference values, with absolute discrepancies less than 0.6% for a self-absorption condition and less than 5% in almost all energies for a cross-absorption condition. We concluded that InterDosi code might be used for dosimetry of internal electron emitters.
摘要:
国际放射防护委员会(ICRP)通过其出版物建议使用体素化体模估算特定吸收分数(SAF),以评估暴露于电离辐射的器官内部吸收的剂量。在目前的工作中,我们报告了使用ICRP成年女性(ICRP-AF)体模计算的大量SAF。基于Geant4的新代码称为InterDosi版本1.0,用于模拟20种不同能量的单能电子,范围从0.005到10MeV,从18个不同的来源器官均匀发射。为了估计169个靶器官/地区的SAF,360MonteCarlo多线程模拟在HPC-MARWAN-CNRST计算网格的32个CPU上运行。将计算出的SAF与使用GATE8.1代码并由OpenDose合作发布的最新结果进行了比较。结果表明,获得的结果与参考值非常吻合,对于自吸收条件,绝对差异小于0.6%,对于交叉吸收条件,几乎所有能量均小于5%。我们得出的结论是,InterDosi代码可用于内部电子发射器的剂量测定。
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