Abstract：
SMARCA4-deficient sarcoma was first reported in the chest and recently in the uterus, but not in the stomach. Here, we present a patient diagnosed with SMARCA4-deficient sarcoma of the stomach, using histochemistry. An emergency operation was performed due to perforation of the tumor. However, one month after the operation, two nodes recurred, and six cycles of combination chemotherapy consisting of adriamycin and ifosfamide were administered. The combination chemotherapy showed a remarkable effect, and complete remission was achieved. The patient was alive without recurrence after 48-month follow-up. SMARCA4-deficient sarcoma is an exceedingly rare tumor with an extremely poor therapeutic response to anticancer drugs. Herein, we present the first case of SMARCA4-deficient sarcoma of the stomach, where a complete response to chemotherapy was achieved.
摘要：
SMARCA4缺陷型肉瘤首次报道在胸部，最近在子宫，但不是在胃里。这里,我们介绍了一个被诊断为缺乏SMARCA4的胃肉瘤的患者，使用组织化学。由于肿瘤穿孔，进行了紧急手术。然而,手术后一个月,两个节点复发，给予阿霉素和异环磷酰胺联合化疗6个周期。联合化疗效果显著，完全缓解。48个月随访后，患者存活无复发。SMARCA4缺陷型肉瘤是一种极其罕见的肿瘤，对抗癌药物的治疗反应极差。在这里，我们介绍了第一例缺乏SMARCA4的胃肉瘤，在那里实现了对化疗的完全反应。
