Abstract：
UNASSIGNED: Drug-resistant epilepsy can occur in patients with intracranial hemorrhage (ICH) caused by hemophilia, there is a paucity of literature reporting the surgical treatment of these patients because of the high risk of bleeding and comprehensive management such as factor replacement during the period of perioperation.
UNASSIGNED: The data of 216 children with drug-resistant epilepsy who underwent surgically treatment in the Pediatric Epilepsy Center of the Capital Institute of Paediatrics were retrospectively reviewed. Seizure response and procedure complications were evaluated. Two cases children with hemophilia underwent surgical treatment at 29 months (case 1) and 6 years of age (case 2) were identified and followed up.
UNASSIGNED: Both children have achieved seizure free without complications such as bleeding or infection after 28 months (case 1) and 21 months (case 2) follow-up.
UNASSIGNED: For children with drug-resistant epilepsy associated with hemophilia, surgery that meets certain conditions can improve the prognosis safely and effectively.
UNASSIGNED: The data of 216 children with drug-resistant epilepsy who underwent surgically treatment in the Pediatric Epilepsy Center of the Capital Institute of Paediatrics were retrospectively reviewed. Seizure response and procedure complications were evaluated. Two cases children with hemophilia underwent surgical treatment at 29 months (case 1) and 6 years of age (case 2) were identified and followed up.
UNASSIGNED: Both children have achieved seizure free without complications such as bleeding or infection after 28 months (case 1) and 21 months (case 2) follow-up.
UNASSIGNED: For children with drug-resistant epilepsy associated with hemophilia, surgery that meets certain conditions can improve the prognosis safely and effectively.
摘要：
背景:耐药性癫痫可发生于血友病所致的颅内出血(ICH),缺乏文献报道这些患者的手术治疗，因为出血风险高，以及围手术期因素置换等综合治疗。方法:回顾性分析在首都儿科研究所小儿癫痫中心接受手术治疗的216例耐药癫痫患儿的资料。评估癫痫发作反应和手术并发症。对2例血友病患儿在29个月（病例1）和6岁（病例2）进行手术治疗，并进行随访。结果:经28个月(病例1)和21个月(病例2)随访,2例患儿均无出血、感染等并发症。结论:对于耐药癫痫合并血友病患儿,符合一定条件的手术可以安全有效地改善预后。
