PDF(Pubmed)
Abstract：
BACKGROUND: Most patients with polio recover from the initial infection, but develop muscle weakness, pain and fatigue after 15-40 years, a condition called post-polio syndrome. Although poliovirus has been almost eliminated, 12-20 million people worldwide still have polio sequelae. The pain is described mainly as nociceptive, but some patients experience neuropathic pain. The aim of this study was to further characterize post-polio pain.
METHODS: A total of 20 patients with post-polio syndrome participated in the study. Physical examination was performed, and questionnaires containing pain drawing and visual analogue scales (VAS) for pain intensity during rest and motion and VAS for fatigue were completed. A walk test was performed to evaluate physical performance.
RESULTS: Pain intensity was high (42/100 on the VAS at rest and 62/100 while moving). The pain was localized in both joints and muscles. Pain in the muscles was of \"deep aching\" character, included \"muscle cramps\" and was located mainly in polio-weakened limbs.
CONCLUSIONS: Muscle pain in patients with post-polio syndrome does not fulfil the criteria for either nociceptive or neuropathic pain; thus, it is suggested that the pain is termed \"post-polio muscular pain\". The intensity of post-polio muscular pain is higher while moving, but does not influence physical function, and is separate from fatigue.
METHODS: A total of 20 patients with post-polio syndrome participated in the study. Physical examination was performed, and questionnaires containing pain drawing and visual analogue scales (VAS) for pain intensity during rest and motion and VAS for fatigue were completed. A walk test was performed to evaluate physical performance.
RESULTS: Pain intensity was high (42/100 on the VAS at rest and 62/100 while moving). The pain was localized in both joints and muscles. Pain in the muscles was of \"deep aching\" character, included \"muscle cramps\" and was located mainly in polio-weakened limbs.
CONCLUSIONS: Muscle pain in patients with post-polio syndrome does not fulfil the criteria for either nociceptive or neuropathic pain; thus, it is suggested that the pain is termed \"post-polio muscular pain\". The intensity of post-polio muscular pain is higher while moving, but does not influence physical function, and is separate from fatigue.
摘要：
背景：大多数脊髓灰质炎患者从最初的感染中恢复，但发展为肌肉无力，15-40年后的疼痛和疲劳，一种叫做脊髓灰质炎后综合症的疾病。虽然脊髓灰质炎病毒已几乎被消灭,全世界仍有1200万至2000万人患有脊髓灰质炎后遗症。疼痛主要被描述为伤害性，但有些患者会出现神经性疼痛.这项研究的目的是进一步表征脊髓灰质炎后疼痛。
方法：共有20名脊髓灰质炎后综合征患者参与了研究。进行了体格检查，完成了包含静息和运动时疼痛强度的疼痛绘图和视觉模拟评分（VAS）以及疲劳的VAS的问卷。进行步行测试以评估物理性能。
结果：疼痛强度高（静息时VAS为42/100，移动时为62/100）。疼痛局限于关节和肌肉。肌肉疼痛是“深痛”的特征，包括“肌肉痉挛”，主要位于脊髓灰质炎弱化的四肢。
结论：脊髓灰质炎后综合征患者的肌肉疼痛不符合伤害性或神经性疼痛的标准；因此，有人认为这种疼痛被称为“脊髓灰质炎后肌肉疼痛”。运动时小儿麻痹症后肌肉疼痛的强度更高，但不影响身体机能，与疲劳是分开的。
方法：共有20名脊髓灰质炎后综合征患者参与了研究。进行了体格检查，完成了包含静息和运动时疼痛强度的疼痛绘图和视觉模拟评分（VAS）以及疲劳的VAS的问卷。进行步行测试以评估物理性能。
结果：疼痛强度高（静息时VAS为42/100，移动时为62/100）。疼痛局限于关节和肌肉。肌肉疼痛是“深痛”的特征，包括“肌肉痉挛”，主要位于脊髓灰质炎弱化的四肢。
结论：脊髓灰质炎后综合征患者的肌肉疼痛不符合伤害性或神经性疼痛的标准；因此，有人认为这种疼痛被称为“脊髓灰质炎后肌肉疼痛”。运动时小儿麻痹症后肌肉疼痛的强度更高，但不影响身体机能，与疲劳是分开的。
