PDF(Pubmed)
Abstract：
COPD has a profound impact on the lives of patients and their partners, but the influence on physical, psychological and social aspects of sexual health has not been reviewed systematically. Searches for studies of the impact of COPD on sexual health were conducted independently by two authors in the databases of PubMed, PsycINFO, Embases, CINAHL, Web of Science, Scopus and The Cochrane Library. English-language quantitative and qualitative studies assessing one or more aspects of sexual health in patients diagnosed with COPD were narratively reviewed and, when possible, subjected to meta-analytic evaluation. A total of 31 studies, including 4 qualitative, were included. Twelve studies assessing erectile dysfunction with the International Index of Erectile Function were subjected to meta-analysis. The pooled prevalence of erectile dysfunction was 74% (95% CI: 68-80%) in a total of 1187 patients with COPD, compared with 56% (37-73%) in 224 age-matched, non-COPD controls. The sexual health outcomes assessed in the remaining studies varied considerably, compromising the comparability of the results. None of the qualitative studies had sexual health as their primary focus. Compared with non-COPD individuals, erectile dysfunction appears to be more prevalent among patients with COPD, but more studies including non-COPD controls are needed to confirm this finding. In addition, the impact of COPD on other physical, psychological and social aspects of sexual health remains unclear due to the lack of comparable assessment methods and study designs.
摘要：
COPD对患者及其伴侣的生活有着深远的影响,但是对身体的影响，尚未对性健康的心理和社会方面进行系统审查。由PubMed数据库中的两名作者独立进行了COPD对性健康影响研究的搜索，PsycINFO,Embases,CINAHL,WebofScience,Scopus和Cochrane图书馆对英语定量和定性研究评估诊断为COPD患者的性健康的一个或多个方面进行了叙述性审查，如果可能,进行元分析评价。共31项研究，包括4个定性，包括在内。使用国际勃起功能指数评估勃起功能障碍的12项研究进行了荟萃分析。在总共1187例COPD患者中，勃起功能障碍的合并患病率为74％（95％CI：68-80％）。与224名年龄匹配者中的56%(37-73%)相比，非COPD对照。其余研究中评估的性健康结果差异很大，影响结果的可比性。没有一项定性研究将性健康作为主要重点。与非COPD个体相比，勃起功能障碍似乎在COPD患者中更为普遍，但需要更多包括非COPD对照组在内的研究来证实这一发现.此外,COPD对其他身体的影响，由于缺乏可比较的评估方法和研究设计,性健康的心理和社会方面仍不清楚.
