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Abstract：
This study aimed to evaluate glare source-induced disk halo size and assess its correlation with higher-order aberrations (HOAs), pupillometry findings, and contrast sensitivity in myopic adults (aged 23.8 ± 4.4 years). In this cross-sectional study, 150 eyes of 150 patients were assessed. All patients underwent routine ophthalmic examinations, wavefront aberrometry, halo size measurement, dynamic pupillometry, and contrast sensitivity tests. Spearman\'s correlation analysis and independent sample t-tests were performed for data analysis. The mean halo radius was 82.5 ± 21.8 and 236.7 ± 52.2 arc min at 5 and 1 cd/m2 luminance levels, respectively. The values were inversely correlated with internal spherical aberration (SA) (r = -0.175, p = 0.032 and r = -0.241, p = 0.003, respectively), but not correlated with spherical equivalent (SE, both p > 0.05). Positive correlations were observed between halo radius and pupil size, contraction amplitude, and dilation speed during pupillary light reflex. Halo radii at 5 and 1 cd/m2 luminance levels were not significantly correlated with the area under the log contrast sensitivity function (r = -0.093, p = 0.258 and r = -0.149, p = 0.069, respectively). The mean halo radius was not clinically different between myopic and healthy eyes at 5 cd/m2 luminance level and did not differ significantly between the high and low-to-moderate myopia at 5 and 1 cd/m2 luminance levels (all p > 0.05). According to a stepwise linear regression model, the internal SA had a negative effect on the halo radius under low photpic condition; the average pupil diameter, internal SA and corneal HOAs played a large role in determining the halo radius under mesopic condition.
摘要：
本研究旨在评估眩光源引起的圆盘光晕大小，并评估其与高阶像差（HOAs）的相关性，瞳孔测量结果,近视成人（23.8±4.4岁）的对比敏感度。在这项横断面研究中，对150例患者的150只眼进行了评估。所有患者均接受常规眼科检查，波前像差测定,光晕尺寸测量,动态瞳孔测量,和对比敏感度测试。数据分析采用Spearman相关分析和独立样本t检验。在5和1cd/m2亮度水平下，平均光晕半径为82.5±21.8和236.7±52.2弧分，分别。这些值与内部球面像差（SA）成反比（分别为r=-0.175，p=0.032和r=-0.241，p=0.003），但与球面当量(SE，两者p>0.05)。光晕半径与瞳孔大小呈正相关，收缩幅度，瞳孔光反射时的扩张速度。在5和1cd/m2亮度水平下的光环半径与对数对比敏感度函数下的面积没有显着相关（分别为r=-0.093，p=0.258和r=-0.149，p=0.069）。在5cd/m2亮度水平下，近视和健康眼睛的平均光晕半径在临床上没有差异，在5和1cd/m2亮度水平下，高度和低至中度近视之间没有显着差异（均p>0.05）。根据逐步线性回归模型，内部SA对低光度条件下的晕圈半径有负面影响；平均瞳孔直径，内部SA和角膜HOA在确定介观条件下的晕圈半径中起着重要作用。
