关键词: Disrupt CAD Intravascular lithotripsy best practice coronary calcified lesion plaque modification

来  源:   DOI:10.15420/icr.2021.14   PDF(Pubmed)

Abstract:
Intravascular lithotripsy (IVL) is a novel approach to lesion preparation of severely calcified plaques in coronary and peripheral vessels. Lithotripsy is delivered by vaporising fluid to create an expanding bubble that generates sonic pressure waves that interact with arterial calcification. Available data indicate that IVL leads to increased vessel compliance before stent implantation with high efficacy and an excellent safety profile. Since it gained the CE mark in 2017, and with improved operator experience, the use of IVL has expanded into more complex clinical situations. This review focuses on the best practice for IVL use in the cath lab, based on 3 years of experience with the technology and the latest scientific data from the Disrupt CAD clinical trials.
摘要:
血管内碎石术(IVL)是一种新颖的方法,可以在冠状动脉和周围血管中制备严重钙化的斑块。碎石术通过蒸发流体以产生膨胀的气泡来递送,该气泡产生与动脉钙化相互作用的声波压力波。现有数据表明,IVL在支架植入前导致血管顺应性增加,具有高功效和优异的安全性。自2017年获得CE标志以来,随着运营商经验的改善,IVL的使用已扩展到更复杂的临床情况。这篇综述的重点是在导管实验室中使用IVL的最佳实践,基于3年的技术经验和来自DisruptCAD临床试验的最新科学数据。
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