Abstract：
To examine the effect of sleep timing intervention on sleep quality, attention, and sleepiness at work among night shift workers with shift work disorder.
We recruited 60 real-life night shift workers through advertisements to participate this cross-over clinical trial. Shift work disorder was confirmed with interview and sleep log. Participants were designated to follow evening sleep (15:00-23:00) and morning sleep (09:00-17:00) schedules in a randomized order. Chronotype was confirmed by the Munich Chronotype Questionnaire. Sleep behaviors and light exposure were recorded using actigraphy. Outcome measures were sleepiness evaluated by the Karolinska Sleepiness Scale, sleep quality evaluated by the Pittsburgh Sleep Quality Index, and attention performance assessed with psychomotor vigilance test. Differences in outcome between the morning and evening sleep schedules were compared using repeated measures ANOVA.
The participants slept for longer durations during evening sleep schedules compared with morning sleep schedules. Lower sleepiness scores, higher sleep quality, and shorter reaction times and less lapse numbers in the psychomotor vigilance test were observed for participants during evening sleep schedules than morning sleep schedules after adjustment for light exposure and sleep duration. Significant interaction effects were observed for reaction time and lapse number between chronotype and sleep schedule, where the differences between sleep schedules were most prominent among those with late chronotypes.
It is recommended that night shift workers with shift work disorder arrange to sleep in the evening instead of the morning for better sleep and attention performance, especially those with late chronotypes.
Sleep Schedule Intervention Study Among Night Shift Workers, https://clinicaltrials.gov/ct2/show/NCT04160572, ClinicalTrials.gov Identifier: NTC04160572.
We recruited 60 real-life night shift workers through advertisements to participate this cross-over clinical trial. Shift work disorder was confirmed with interview and sleep log. Participants were designated to follow evening sleep (15:00-23:00) and morning sleep (09:00-17:00) schedules in a randomized order. Chronotype was confirmed by the Munich Chronotype Questionnaire. Sleep behaviors and light exposure were recorded using actigraphy. Outcome measures were sleepiness evaluated by the Karolinska Sleepiness Scale, sleep quality evaluated by the Pittsburgh Sleep Quality Index, and attention performance assessed with psychomotor vigilance test. Differences in outcome between the morning and evening sleep schedules were compared using repeated measures ANOVA.
The participants slept for longer durations during evening sleep schedules compared with morning sleep schedules. Lower sleepiness scores, higher sleep quality, and shorter reaction times and less lapse numbers in the psychomotor vigilance test were observed for participants during evening sleep schedules than morning sleep schedules after adjustment for light exposure and sleep duration. Significant interaction effects were observed for reaction time and lapse number between chronotype and sleep schedule, where the differences between sleep schedules were most prominent among those with late chronotypes.
It is recommended that night shift workers with shift work disorder arrange to sleep in the evening instead of the morning for better sleep and attention performance, especially those with late chronotypes.
Sleep Schedule Intervention Study Among Night Shift Workers, https://clinicaltrials.gov/ct2/show/NCT04160572, ClinicalTrials.gov Identifier: NTC04160572.
摘要：
为了研究睡眠定时干预对睡眠质量的影响，注意,夜班工人倒班工作时的嗜睡。
我们通过广告招募了60名现实生活中的夜班工人参加这项交叉临床试验。轮班工作障碍通过访谈和睡眠日志得到证实。参与者被指定以随机顺序遵循晚上睡眠(15:00-23:00)和早上睡眠(09:00-17:00)时间表。时序型由慕尼黑时序型问卷确认。使用活动记录记录睡眠行为和光照。结果指标是通过Karolinska嗜睡量表评估嗜睡，匹兹堡睡眠质量指数评估的睡眠质量，和精神运动警觉测验评估的注意力表现。使用重复测量ANOVA比较早晨和晚上睡眠时间表之间的结果差异。
与早晨的睡眠时间表相比，参与者在晚上的睡眠时间表中睡眠时间更长。较低的嗜睡分数，更高的睡眠质量，在调整光照和睡眠持续时间后，在晚上的睡眠时间表中，参与者的反应时间更短，精神运动警觉测试中的失误次数少于早上的睡眠时间表。观察到时间型和睡眠时间表之间的反应时间和流逝数的显着交互效应，其中睡眠时间表之间的差异在具有晚期慢性型的人群中最为突出。
建议有倒班工作障碍的夜班工人安排在晚上而不是早上睡觉，以获得更好的睡眠和注意力表现，尤其是那些具有晚期时间型的人。
夜班工人的睡眠时间表干预研究，https://clinicaltrials.gov/ct2/show/NCT04160572,ClinicalTrials.gov标识符:NTC04160572。
我们通过广告招募了60名现实生活中的夜班工人参加这项交叉临床试验。轮班工作障碍通过访谈和睡眠日志得到证实。参与者被指定以随机顺序遵循晚上睡眠(15:00-23:00)和早上睡眠(09:00-17:00)时间表。时序型由慕尼黑时序型问卷确认。使用活动记录记录睡眠行为和光照。结果指标是通过Karolinska嗜睡量表评估嗜睡，匹兹堡睡眠质量指数评估的睡眠质量，和精神运动警觉测验评估的注意力表现。使用重复测量ANOVA比较早晨和晚上睡眠时间表之间的结果差异。
与早晨的睡眠时间表相比，参与者在晚上的睡眠时间表中睡眠时间更长。较低的嗜睡分数，更高的睡眠质量，在调整光照和睡眠持续时间后，在晚上的睡眠时间表中，参与者的反应时间更短，精神运动警觉测试中的失误次数少于早上的睡眠时间表。观察到时间型和睡眠时间表之间的反应时间和流逝数的显着交互效应，其中睡眠时间表之间的差异在具有晚期慢性型的人群中最为突出。
建议有倒班工作障碍的夜班工人安排在晚上而不是早上睡觉，以获得更好的睡眠和注意力表现，尤其是那些具有晚期时间型的人。
夜班工人的睡眠时间表干预研究，https://clinicaltrials.gov/ct2/show/NCT04160572,ClinicalTrials.gov标识符:NTC04160572。
