Abstract：
OBJECTIVE: The study aimed to evaluate the treatment efficacy of the combination of Da-Cheng-Qi Decoction (DCQD) injected into the jejunum and as an enema in patients with critical diseases with paralytic ileus.
METHODS: In our double-blind randomized controlled study, 114 critically ill patients with paralytic ileus were divided into 2 groups. The control group received conventional medical treatment, and the DCQD group was treated with integrated traditional Chinese medicine (TCM) and Western medicine. The intra-abdominal pressure (IAP), recovery of gastrointestinal (GI) function, clinical efficacy and intensive care unit (ICU) stay in the 2 groups were recorded and compared.
RESULTS: The IAP in the DCQD group was lower than in the control group (P < .05). The recovery of GI function and clinical efficacy rate in the DCQD group were significantly better than in the control group (P < .05, respectively).
CONCLUSIONS: DCQD may be an effective method for treating patients with critical diseases with paralytic ileus and is worthy of clinical application.
METHODS: In our double-blind randomized controlled study, 114 critically ill patients with paralytic ileus were divided into 2 groups. The control group received conventional medical treatment, and the DCQD group was treated with integrated traditional Chinese medicine (TCM) and Western medicine. The intra-abdominal pressure (IAP), recovery of gastrointestinal (GI) function, clinical efficacy and intensive care unit (ICU) stay in the 2 groups were recorded and compared.
RESULTS: The IAP in the DCQD group was lower than in the control group (P < .05). The recovery of GI function and clinical efficacy rate in the DCQD group were significantly better than in the control group (P < .05, respectively).
CONCLUSIONS: DCQD may be an effective method for treating patients with critical diseases with paralytic ileus and is worthy of clinical application.
摘要：
目的：本研究旨在评价大承气汤(DCQD)空肠内注射联合灌肠治疗危重疾病麻痹性肠梗阻的疗效。
方法：在我们的双盲随机对照研究中，将114例危重的麻痹性肠梗阻患者分为2组。对照组给予常规药物治疗,DCQD组采用中西医结合治疗。腹内压（IAP），胃肠道（GI）功能的恢复，记录并比较2组患者的临床疗效和重症监护病房(ICU)住院时间。
结果：DCQD组的IAP低于对照组（P<0.05）。DCQD组患者的胃肠功能恢复情况和临床有效率均明显优于对照组(P<0.05)。
结论：DCQD可能是治疗危重症麻痹性肠梗阻的有效方法，值得临床推广应用。
方法：在我们的双盲随机对照研究中，将114例危重的麻痹性肠梗阻患者分为2组。对照组给予常规药物治疗,DCQD组采用中西医结合治疗。腹内压（IAP），胃肠道（GI）功能的恢复，记录并比较2组患者的临床疗效和重症监护病房(ICU)住院时间。
结果：DCQD组的IAP低于对照组（P<0.05）。DCQD组患者的胃肠功能恢复情况和临床有效率均明显优于对照组(P<0.05)。
结论：DCQD可能是治疗危重症麻痹性肠梗阻的有效方法，值得临床推广应用。
