Abstract：
BACKGROUND: Hyaluronic acid (HA) is an effective dermal filler for facial rejuvenation. This study aimed to observe the clinical efficacy of HA injection for lip augmentation in Chinese patients.
METHODS: From May 2019 to April 2020, 70 patients with lip fullness scale (LPS) ≤3 underwent local HA injection using the \"three-point\" injection technique. All patients were followed up to observe the clinical efficacy, LPS, adverse events, and complications.
RESULTS: All 70 patients were followed up for 12 months. Statistically significant improvements were observed in the height of lips within 6-9 months post-treatment (p < 0.05). The LFS improved significantly at follow-up compared with baseline (p < 0.05). Local redness occurred in two patients, and serious swelling occurred in three patients. These adverse events were generally tolerated and disappeared gradually within 1 week. No other serious adverse events and complications were reported in the remaining patients.
CONCLUSIONS: Hyaluronic acid injection can be used for lip augmentation in the Chinese population. The \"three-point\" technique is simple, safe, and effective and does not cause serious complications.
METHODS: From May 2019 to April 2020, 70 patients with lip fullness scale (LPS) ≤3 underwent local HA injection using the \"three-point\" injection technique. All patients were followed up to observe the clinical efficacy, LPS, adverse events, and complications.
RESULTS: All 70 patients were followed up for 12 months. Statistically significant improvements were observed in the height of lips within 6-9 months post-treatment (p < 0.05). The LFS improved significantly at follow-up compared with baseline (p < 0.05). Local redness occurred in two patients, and serious swelling occurred in three patients. These adverse events were generally tolerated and disappeared gradually within 1 week. No other serious adverse events and complications were reported in the remaining patients.
CONCLUSIONS: Hyaluronic acid injection can be used for lip augmentation in the Chinese population. The \"three-point\" technique is simple, safe, and effective and does not cause serious complications.
摘要：
背景:透明质酸(HA)是用于面部年轻化的有效真皮填充剂。本研究旨在观察HA注射液在中国患者中用于丰唇的临床疗效。
方法：从2019年5月至2020年4月，使用“三点”注射技术对70例嘴唇丰满量表（LPS）≤3的患者进行了局部HA注射。对所有患者进行随访,观察临床疗效,LPS,不良事件,和并发症。
结果：70例患者均获12个月随访。在治疗后6-9个月内观察到嘴唇高度的统计学显着改善（p<0.05）。随访时LFS较基线显著改善(p<0.05)。两名患者出现局部红肿,3例患者出现严重肿胀。这些不良事件通常是耐受的，并在1周内逐渐消失。其余患者未报告其他严重不良事件和并发症。
结论：透明质酸注射液可用于中国人群的丰唇。“三点”技术很简单，安全,并且有效，不会引起严重的并发症。
方法：从2019年5月至2020年4月，使用“三点”注射技术对70例嘴唇丰满量表（LPS）≤3的患者进行了局部HA注射。对所有患者进行随访,观察临床疗效,LPS,不良事件,和并发症。
结果：70例患者均获12个月随访。在治疗后6-9个月内观察到嘴唇高度的统计学显着改善（p<0.05）。随访时LFS较基线显著改善(p<0.05)。两名患者出现局部红肿,3例患者出现严重肿胀。这些不良事件通常是耐受的，并在1周内逐渐消失。其余患者未报告其他严重不良事件和并发症。
结论：透明质酸注射液可用于中国人群的丰唇。“三点”技术很简单，安全,并且有效，不会引起严重的并发症。
