PDF(Pubmed)
Abstract：
A 68-year-old woman with stage III colon cancer status after right hemicolectomy and adjuvant FOLFOX (5-fluorouracil/leucovorin/oxaliplatin) chemotherapy was hospitalized for melena and found to have new-onset esophageal and gastric varices on esophagogastroduodenoscopy. Her workup did not reveal an underlying liver disease, but her liver biopsy showed noncirrhotic portal hypertension from obliterative portal venopathy (OPV). The development of OPV is likely from her use of oxaliplatin-based chemotherapy.
摘要：
一名68岁的女性，在右半结肠切除术和辅助FOLFOX（5-氟尿嘧啶/亚叶酸钙/奥沙利铂）化疗后患有III期结肠癌，因黑便住院，并在食管胃十二指肠镜检查中发现新发食管和胃静脉曲张。她的检查没有发现潜在的肝脏疾病，但她的肝活检显示闭塞性门静脉病（OPV）引起的非肝硬化门静脉高压。OPV的发展可能来自她使用基于奥沙利铂的化疗。
