PDF(Pubmed)
Abstract：
In biomedical, life or environmental science research, two different strategies exist depending on the starting point of the researchers: \"what makes us ill? \" or \"what makes us healthy?\". Indeed, a risk-based strategy (RBS) attempts to minimize risk factors increasing the likelihood of developing a disease, while an asset-based strategy (ABS) attempts to promote and strengthen the factors that support good health and wellbeing. We provided an up-to-date overview of both research strategies in peer-reviewed scientific literature, in the fields of human health, animal and plant health and ecosystem health, to fit with the One Health framework. More particularly, we focused on human health by studying publications related to the COVID-19 at the beginning of the pandemic.
A rapid review of research science literature was carried out to identify in the PubMed/MEDLINE database the proportion of peer-reviewed articles adopting either a RBS or an ABS, in the main global environment fields from January 01, 1900 to December 31, 2019 and, related to COVID-19, from December 1, 2019 to May 31, 2020.
The number of published articles resulting from our search was 1,957,905, including 91.3% with an RBS and 8.7% with an ABS. When examining each field, we found that only 10.5% of human health articles deal with ABS, 5.5% for animal health, 2.2% for ecosystem health, 1.0% for plant health and 2.7% for environmental media. We noted that articles adopting both strategies were published in all health fields. Among the articles concerning COVID-19, 5,854 (55.9%), 542 articles (5.2%) adopted RBS and ABS, respectively, while 4069 (38.9%) simultaneously presenting both strategies.
Our results have allowed us to take stock of the biomedical research strategies prioritized during the twentieth century. It seems highly likely that the two strategies we have analyzed can now be chosen in such a way as to promote a balance in public health measures, at every level to guide One Health interventions aimed at helping people, animals, and plants to lead healthier lives.
A rapid review of research science literature was carried out to identify in the PubMed/MEDLINE database the proportion of peer-reviewed articles adopting either a RBS or an ABS, in the main global environment fields from January 01, 1900 to December 31, 2019 and, related to COVID-19, from December 1, 2019 to May 31, 2020.
The number of published articles resulting from our search was 1,957,905, including 91.3% with an RBS and 8.7% with an ABS. When examining each field, we found that only 10.5% of human health articles deal with ABS, 5.5% for animal health, 2.2% for ecosystem health, 1.0% for plant health and 2.7% for environmental media. We noted that articles adopting both strategies were published in all health fields. Among the articles concerning COVID-19, 5,854 (55.9%), 542 articles (5.2%) adopted RBS and ABS, respectively, while 4069 (38.9%) simultaneously presenting both strategies.
Our results have allowed us to take stock of the biomedical research strategies prioritized during the twentieth century. It seems highly likely that the two strategies we have analyzed can now be chosen in such a way as to promote a balance in public health measures, at every level to guide One Health interventions aimed at helping people, animals, and plants to lead healthier lives.
摘要：
在生物医学领域,生命或环境科学研究，根据研究人员的出发点，存在两种不同的策略：“是什么让我们生病？”或“是什么让我们健康？”。的确,基于风险的策略（RBS）试图将增加疾病发展可能性的风险因素降至最低。而基于资产的战略（ABS）试图促进和加强支持良好健康和福祉的因素。我们在同行评审的科学文献中提供了两种研究策略的最新概述，在人类健康领域，动植物健康和生态系统健康，以适应一个健康框架。更具体地说,我们通过研究大流行开始时与COVID-19相关的出版物来关注人类健康。
对研究科学文献进行了快速审查，以在PubMed/MEDLINE数据库中确定采用RBS或ABS的同行评审文章的比例，在1900年1月1日至2019年12月31日的主要全球环境领域，与COVID-19相关，从2019年12月1日至2020年5月31日。
我们搜索的已发表文章数量为1,957,905，其中RBS占91.3％，ABS占8.7％。检查每个字段时，我们发现只有10.5%的健康文章涉及ABS，动物健康5.5%，生态系统健康2.2%，1.0％用于植物健康，2.7％用于环境介质。我们注意到，所有卫生领域都发表了采用这两种策略的文章。在有关COVID-19的文章中，5854篇(55.9%)，542篇(5.2%)采用了RBS和ABS，分别,而4069（38.9%）同时提出两种策略。
我们的研究结果使我们能够评估20世纪优先考虑的生物医学研究策略。我们分析过的这两种策略现在似乎很有可能被选择，以促进公共卫生措施的平衡，在各个层面指导一个健康干预措施，旨在帮助人们，动物,和植物过上更健康的生活。
对研究科学文献进行了快速审查，以在PubMed/MEDLINE数据库中确定采用RBS或ABS的同行评审文章的比例，在1900年1月1日至2019年12月31日的主要全球环境领域，与COVID-19相关，从2019年12月1日至2020年5月31日。
我们搜索的已发表文章数量为1,957,905，其中RBS占91.3％，ABS占8.7％。检查每个字段时，我们发现只有10.5%的健康文章涉及ABS，动物健康5.5%，生态系统健康2.2%，1.0％用于植物健康，2.7％用于环境介质。我们注意到，所有卫生领域都发表了采用这两种策略的文章。在有关COVID-19的文章中，5854篇(55.9%)，542篇(5.2%)采用了RBS和ABS，分别,而4069（38.9%）同时提出两种策略。
我们的研究结果使我们能够评估20世纪优先考虑的生物医学研究策略。我们分析过的这两种策略现在似乎很有可能被选择，以促进公共卫生措施的平衡，在各个层面指导一个健康干预措施，旨在帮助人们，动物,和植物过上更健康的生活。
