Olaparib 和 Pembrolizumab 治疗具有种系 BRCA1 突变和高肿瘤突变负担的胰腺腺癌 : 病例报告和文献复习。
Mesh : Adenocarcinoma / drug therapy genetics Aged Antibodies, Monoclonal, Humanized / therapeutic use Antineoplastic Agents / therapeutic use BRCA1 Protein / genetics Germ Cells Humans Male Mutation Pancreatic Neoplasms / drug therapy genetics Phthalazines / therapeutic use Piperazines / therapeutic use Treatment Outcome Tumor Burden