Abstract:
Angiomyolipoma, a perivascular epithelioid cell tumour, is easily identifiable as a benign tumour in the kidneys. However, when occurring in extrarenal sites it can mimic malignancy (Cancer Cytopathol. 2017;125:257). Pathologists must be aware of the classical morphological features of this lesion, its pitfalls in extrarenal sites, and the need for immunohistochemistry in order to establish the correct diagnosis (World J Gastroenterol. 2000;6:608). We report a case of angiomyolipoma with extramedullary hematopoiesis presenting as a large hepatic mass, diagnosed by cytology through endoscopic ultrasound guided fine needle aspiration. Our case exemplifies the classic cytological findings that are important in the differentiation between hepatic angiomyolipoma (HAML) and differentials in this organ such as hepatocellular carcinoma (HCC) and focal nodular hyperplasia. A brief literature review and comparison of significant features between HAML and HCC are presented.
摘要:
血管平滑肌脂肪瘤,血管周围上皮样细胞瘤,很容易识别为肾脏中的良性肿瘤。然而,当发生在肾外部位时,它可以模拟恶性肿瘤(癌症细胞病理。2017;125:257)。病理学家必须意识到这种病变的经典形态特征,它在外地的陷阱,以及需要进行免疫组织化学以建立正确的诊断(WorldJGastroenterol。2000;6:608)。我们报告了一例伴有髓外造血的血管平滑肌脂肪瘤,表现为巨大的肝脏肿块,通过内窥镜超声引导的细针穿刺细胞学诊断。我们的案例说明了经典的细胞学发现,这些发现对于区分肝血管平滑肌脂肪瘤(HAML)和该器官的差异(例如肝细胞癌(HCC)和局灶性结节增生)至关重要。简要回顾了HAML和HCC之间的重要特征,并进行了比较。