PDF(Pubmed)
Abstract：
Synthetic cells, which mimic cellular function within a minimal compartment, are finding wide application, for instance in studying cellular communication and as delivery devices to living cells. However, to fully realise the potential of synthetic cells, control of their function is vital. An array of tools has already been developed to control the communication of synthetic cells to neighbouring synthetic cells or living cells. These tools use either chemical inputs, such as small molecules, or physical inputs, such as light. Here, we examine these current methods of controlling synthetic cell communication and consider alternative mechanisms for future use.
摘要：
合成细胞,在最小的隔间内模仿细胞功能，正在寻找广泛应用，例如，在研究细胞通讯和作为活细胞的输送装置。然而,为了充分意识到合成细胞的潜力，控制其功能至关重要。已经开发了一系列工具来控制合成细胞与相邻合成细胞或活细胞的通信。这些工具使用化学输入，比如小分子，或物理输入，如光。这里,我们研究了这些目前控制合成细胞通讯的方法，并考虑了未来使用的替代机制。
