PDF(Pubmed)
Abstract：
Introduction Kligman\'s formula is a topical triple combination consisting of hydroquinone, tretinoin, and topical corticosteroid. It has recently become widely popular among the general population for different purposes. Its improper use can lead to unsatisfactory results and unpleasant side effects. Aim This study aimed to assess the attitude, satisfaction, and complications related to topical usage of Kligman\'s formula among the general population in Saudi Arabia. Materials and methods A cross-sectional study was conducted among the general population of Saudi Arabia. A self-administered questionnaire was distributed among the targeted population using an online survey. The questionnaire includes socio-demographic characteristics, assessment of attitude, and satisfaction in using Kligman\'s formula. Data were tabulated and cleaned, and all statistical analyses were performed. Results A total of 292 participants met the inclusion criteria (26 males vs. 266 females) with a mean age of 26.9 (SD 7.71) years. Nearly 40% of participants showed a positive attitude in using Kligman\'s formula, while 46.9% were satisfied with using it. The most common reason for using Kligman\'s formula was to lighten the skin (55.8%), while skin redness was the most commonly reported adverse effect. Factors associated with increased attitude and satisfaction were using Kligman\'s formula based on a doctor\'s prescription and regular follow-up with a dermatologist. Conclusion The general population showed an improper attitude toward using Kligman\'s formula. However, a better attitude and satisfaction rate can be seen among those using Kligman\'s formula with prescription and those who regularly visit a dermatologist.
摘要：
介绍Kligman的配方是由对苯二酚组成的局部三联组合，维甲酸,和外用皮质类固醇.由于不同的目的，它最近在普通人群中广泛流行。其使用不当会导致不满意的结果和令人不快的副作用。目的本研究旨在评估这种态度，满意,沙特阿拉伯普通人群中与局部使用Kligman配方相关的并发症。材料和方法在沙特阿拉伯的一般人群中进行了横断面研究。使用在线调查在目标人群中分发了一份自我管理的问卷。问卷包括社会人口学特征，态度评估，以及使用Kligman公式的满意度。数据被制表和清理，并进行了所有统计分析.结果共有292例参与者符合纳入标准（男性26例，男性与266名女性），平均年龄26.9（SD7.71）岁。近40%的参与者在使用Kligman公式时表现出积极的态度，46.9%的人对使用满意。使用Kligman配方的最常见原因是为了减轻皮肤（55.8％），而皮肤发红是最常见的不良反应。与态度和满意度增加相关的因素是根据医生的处方和皮肤科医生的定期随访使用Kligman配方。结论一般人群对使用Kligman公式的态度不正确。然而,一个更好的态度和满意度可以看到那些使用Kligman的配方处方和那些经常访问皮肤科医生。
