Abstract：
BACKGROUND: Cancer-related fatigue (CRF) is one of the most common complications of cancer. The incidence of CRF is higher than 80%. The NCCN describes it as a distressing, persistent, subjective sense of physical, emotional, and/or cognitive tiredness or exhaustion. It exists in cancer treatment and may last for months or even years. CRF seriously impairs patients\' quality of life. However, there is still a lack of effective drug treatment. Astragalus can improve patients\' fatigue state in the clinical practice of Chinese medicine. There are some studies on the treatment of CRF with Astragalus-containing prescription. However, there is no comprehensive analysis of them. We will perform a meta-analyze on the therapeutic effect of Astragalus-containing prescription for CRF.
METHODS: We will search China National Knowledge Infrastructure, Chinese Scientific Journal Database, Chinese Biomedical Literature Database, Wanfang Database, EMBASE, MEDLINE, and the Cochrane Registry of Controlled Clinical Trials. The information is from the databases\' inception to December 15, 2021. According to the Cochrane Handbook for Systematic Reviews of Interventions, data extraction and processing are carried out. Review Manager 5.4 is used for meta-analysis.
RESULTS: We will take the severity of CRF as the primary outcome.
CONCLUSIONS: We will conduct a meta-analysis to evaluate the efficacy of Astragalus-containing prescriptions in treating CRF.
METHODS: We will search China National Knowledge Infrastructure, Chinese Scientific Journal Database, Chinese Biomedical Literature Database, Wanfang Database, EMBASE, MEDLINE, and the Cochrane Registry of Controlled Clinical Trials. The information is from the databases\' inception to December 15, 2021. According to the Cochrane Handbook for Systematic Reviews of Interventions, data extraction and processing are carried out. Review Manager 5.4 is used for meta-analysis.
RESULTS: We will take the severity of CRF as the primary outcome.
CONCLUSIONS: We will conduct a meta-analysis to evaluate the efficacy of Astragalus-containing prescriptions in treating CRF.
摘要：
背景：癌症相关性疲劳（CRF）是癌症最常见的并发症之一。CRF的发生率高于80%。NCCN将其描述为令人痛苦的，持久性,身体的主观感觉，情感,和/或认知疲劳或疲惫。它存在于癌症治疗中，可能持续数月甚至数年。CRF严重损害患者的生活质量。然而,仍然缺乏有效的药物治疗。黄芪在中医临床实践中可以改善患者的疲劳状态。有一些关于含黄芪方剂治疗CRF的研究。然而,没有对它们进行全面的分析。我们将对含黄芪的CRF处方的治疗效果进行荟萃分析。
方法：我们将搜索中国国家知识基础设施，中国科学期刊数据库,中国生物医学文献数据库,万方数据库,EMBASE,MEDLINE,和Cochrane对照临床试验注册中心。这些信息是从数据库开始到2021年12月15日。根据Cochrane干预措施系统审查手册，进行数据提取和处理。ReviewManager5.4用于荟萃分析。
结果：我们将CRF的严重程度作为主要结果。
结论：我们将进行荟萃分析，以评估含黄芪的方剂治疗CRF的疗效。
方法：我们将搜索中国国家知识基础设施，中国科学期刊数据库,中国生物医学文献数据库,万方数据库,EMBASE,MEDLINE,和Cochrane对照临床试验注册中心。这些信息是从数据库开始到2021年12月15日。根据Cochrane干预措施系统审查手册，进行数据提取和处理。ReviewManager5.4用于荟萃分析。
结果：我们将CRF的严重程度作为主要结果。
结论：我们将进行荟萃分析，以评估含黄芪的方剂治疗CRF的疗效。
