乙型肝炎病毒感染中的体液免疫 : HBV 中的 B 。
关键词: ADCC, antibody-dependent cellular cytotoxicity ALT, alanine aminotransferase AtMBCs, atypical memory B cells B cells CHB, chronic hepatitis B DEGs, differentially expressed genes ENEG, HBeAg-negative chronic hepatitis Fcrl5, Fc receptor-like 5 HBV-ALF, HBV-induced acute liver failure HBcAb, hepatitis B core antibodies HBcrAg, hepatitis B core-related antigen HBsAb, hepatitis B surface antibodies HC, healthy controls HbeAb, hepatitis B e antibodies IL-, interleukin- MBC, memory B cells NA s, nucleos(t)ide analogues ORF, open reading frame PBMC, peripheral blood mononuclear cells PD-1, programmed cell death 1 TLR, Toll-like receptor antibodies cccDNA, covalently closed circular DNA flares global B cells hepatitis B virus hepatitis B-specific B cells iMATE, intrahepatic myeloid-cell aggregates ADCC, antibody-dependent cellular cytotoxicity ALT, alanine aminotransferase AtMBCs, atypical memory B cells B cells CHB, chronic hepatitis B DEGs, differentially expressed genes ENEG, HBeAg-negative chronic hepatitis Fcrl5, Fc receptor-like 5 HBV-ALF, HBV-induced acute liver failure HBcAb, hepatitis B core antibodies HBcrAg, hepatitis B core-related antigen HBsAb, hepatitis B surface antibodies HC, healthy controls HbeAb, hepatitis B e antibodies IL-, interleukin- MBC, memory B cells NA s, nucleos(t)ide analogues ORF, open reading frame PBMC, peripheral blood mononuclear cells PD-1, programmed cell death 1 TLR, Toll-like receptor antibodies cccDNA, covalently closed circular DNA flares global B cells hepatitis B virus hepatitis B-specific B cells iMATE, intrahepatic myeloid-cell aggregates
来 源:
DOI:10.1016/j.jhepr.2021.100398
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