关键词: ELISA IHA Pakistan cystic echinococcosis hydatic cysts hydatid cysts seropositivity

来  源:   DOI:10.3390/pathogens11010029

Abstract:
Human cystic echinococcosis (CE) is a zoonotic disease caused by the larval stage of Echinococcus granulosus sensu lato that causes economic losses by affecting livestock and also poses a public health threat worldwide. The present study is the first retrospective report on the seroprevalence of anti-E. granulosus antibodies in humans in Pakistan. The study used data from 93 blood analysis reports of patients suspected of having CE from different medical centers in Lahore, Pakistan. Out of 93 sera samples, 20 (21.5%) were seropositive, and higher seropositivity (17.2%) was recorded with the indirect hemagglutination test (IHA) than with enzyme-linked immunosorbent assay (ELISA). The findings indicated that age, gender, and year had no significant relationship with the seropositivity of CE. The current study provides directions towards the management of the disease in the near future in Pakistan.
摘要:
人囊性包虫病(CE)是一种由细粒棘球蚴幼虫期引起的人畜共患疾病,通过影响牲畜造成经济损失,并在全球范围内构成公共卫生威胁。本研究是关于抗E.巴基斯坦人类的颗粒抗体。该研究使用了来自拉合尔不同医疗中心的93份疑似CE患者的血液分析报告的数据,巴基斯坦。在93份血清样本中,20例(21.5%)血清阳性,间接血凝试验(IHA)的血清阳性率(17.2%)高于酶联免疫吸附测定(ELISA)。研究结果表明,年龄,性别,和年份与CE的血清阳性没有显着关系。目前的研究为巴基斯坦近期的疾病管理提供了方向。
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