Abstract：
BACKGROUND: For resectable esophageal cancer (EC), it remains controversial whether to place percutaneous endoscopic gastrostomy (PEG) before the curative surgery to provide nutritional support during the neoadjuvant therapy.
OBJECTIVE: To compare surgical outcomes for patients who received preoperative PEG and those without PEG placement (No-PEG) insertion prior to surgery in a potentially operable EC.
METHODS: A comprehensive literature search was conducted to identify randomized and non-randomized studies comparing PEG and No-PEG groups.
RESULTS: Four retrospective studies with a total number of 1,027 patients were identified and included in this meta-analysis. The differences in anastomotic leakage, anastomotic stricture, morbidity, pulmonary complications, wound infection, and hospital stay were not statistically significant between the two groups. Operation time was significantly shorter in the PEG group. There was no PEG-related gastric conduit failure and no leak from the PEG site in the PEG group.
CONCLUSIONS: We conclude preoperative PEG for resectable EC is a safe procedure with no adverse effect on the gastric tube construction and anastomosis, it can be selectively inserted for EC patients with marked weight loss and malnutrition or those at risk of developing malnutrition during neoadjuvant therapy.
OBJECTIVE: To compare surgical outcomes for patients who received preoperative PEG and those without PEG placement (No-PEG) insertion prior to surgery in a potentially operable EC.
METHODS: A comprehensive literature search was conducted to identify randomized and non-randomized studies comparing PEG and No-PEG groups.
RESULTS: Four retrospective studies with a total number of 1,027 patients were identified and included in this meta-analysis. The differences in anastomotic leakage, anastomotic stricture, morbidity, pulmonary complications, wound infection, and hospital stay were not statistically significant between the two groups. Operation time was significantly shorter in the PEG group. There was no PEG-related gastric conduit failure and no leak from the PEG site in the PEG group.
CONCLUSIONS: We conclude preoperative PEG for resectable EC is a safe procedure with no adverse effect on the gastric tube construction and anastomosis, it can be selectively inserted for EC patients with marked weight loss and malnutrition or those at risk of developing malnutrition during neoadjuvant therapy.
摘要：
背景：对于可切除的食管癌（EC），是否在根治性手术前进行经皮内镜胃造瘘术(PEG)以在新辅助治疗期间提供营养支持仍存在争议.
目的：比较在可能可手术的EC中接受术前PEG和未插入PEG（No-PEG）的患者的手术结果。
方法：进行了全面的文献检索，以确定比较PEG组和No-PEG组的随机和非随机研究。
结果：确定了4项回顾性研究，共1,027名患者，并纳入本荟萃分析。吻合口漏的差异，吻合口狭窄,发病率，肺部并发症,伤口感染,两组住院时间无统计学意义。PEG组手术时间明显缩短。在PEG组中,没有PEG相关的胃导管衰竭,也没有PEG位点的渗漏。
结论：我们得出结论，术前PEG治疗可切除EC是一种安全的手术，对胃管结构和吻合无不良影响。对于有明显体重减轻和营养不良的EC患者或在新辅助治疗期间有发生营养不良风险的患者,可以选择性地插入该药物.
目的：比较在可能可手术的EC中接受术前PEG和未插入PEG（No-PEG）的患者的手术结果。
方法：进行了全面的文献检索，以确定比较PEG组和No-PEG组的随机和非随机研究。
结果：确定了4项回顾性研究，共1,027名患者，并纳入本荟萃分析。吻合口漏的差异，吻合口狭窄,发病率，肺部并发症,伤口感染,两组住院时间无统计学意义。PEG组手术时间明显缩短。在PEG组中,没有PEG相关的胃导管衰竭,也没有PEG位点的渗漏。
结论：我们得出结论，术前PEG治疗可切除EC是一种安全的手术，对胃管结构和吻合无不良影响。对于有明显体重减轻和营养不良的EC患者或在新辅助治疗期间有发生营养不良风险的患者,可以选择性地插入该药物.
