METHODS: A 61-year-old male with a history of gout and chronic colchicine intake was admitted to our Emergency Department due to numbness and weakness of the lower limbs. The patient reported a history of colchicine intake for 23 years. After thorough examination, he was diagnosed with colchicine poisoning, manifesting as neuromyopathy, multiple gastric ulcers and myelosuppression. We advised him to stop taking colchicine and drinking alcohol. We also provided a prescription of lansoprazole and mecobalamin, and then asked him to return to the clinic for re-examination. The patient was followed up for 3-mo during which time his gout symptoms were controlled to the point where he was asymptomatic.
CONCLUSIONS: Colchicine overdose can mimic the clinical manifestations of several conditions. Physicians easily pay attention to the disease while ignoring the cause of the disease. Thus, the patient\'s medication history should never be ignored.
方法:一名61岁男性,有痛风和慢性秋水仙碱摄入史,由于下肢麻木和无力,被纳入急诊科。患者报告有23年的秋水仙碱摄入史。经过彻底检查,他被诊断为秋水仙碱中毒,表现为神经肌病,多发性胃溃疡和骨髓抑制。我们建议他停止服用秋水仙碱和饮酒。我们还提供了兰索拉唑和甲钴胺的处方,然后让他回到诊所重新检查。对患者进行了3个月的随访,在此期间他的痛风症状被控制到无症状的程度。
结论:秋水仙碱过量可以模拟几种情况的临床表现。医生容易注意疾病,而忽略疾病的原因。因此,患者的用药史不容忽视。