BarH 样同源异型框 2 抑制角蛋白 16 的转录并影响 Ras 信号通路以抑制鼻咽癌进展。
关键词: BARX2 KRT16 Nasopharyngeal carcinoma proliferation the Ras signaling pathway BARX2 KRT16 Nasopharyngeal carcinoma proliferation the Ras signaling pathway
Mesh : Animals Cell Line, Tumor Cell Movement / genetics Cell Proliferation / genetics Disease Progression Down-Regulation / genetics Female Gene Expression Regulation, Neoplastic Genes, ras / physiology Homeodomain Proteins / physiology Humans Keratin-16 / genetics Mice Mice, Inbred BALB C Mice, Nude Nasopharyngeal Carcinoma / genetics pathology Nasopharyngeal Neoplasms / genetics pathology Signal Transduction / genetics Animals Cell Line, Tumor Cell Movement / genetics Cell Proliferation / genetics Disease Progression Down-Regulation / genetics Female Gene Expression Regulation, Neoplastic Genes, ras / physiology Homeodomain Proteins / physiology Humans Keratin-16 / genetics Mice Mice, Inbred BALB C Mice, Nude Nasopharyngeal Carcinoma / genetics pathology Nasopharyngeal Neoplasms / genetics pathology Signal Transduction / genetics
来 源: DOI:10.1080/21655979.2022.2026549