Abstract：
BACKGROUND: Hair transplantation (HT) is a safe and rewarding procedure for a patient as well as the surgeon. Clonidine may be a good adjuvant in HT because of its analgesic, anxiolytic, and sedative effects.
OBJECTIVE: To study efficacy of Clonidine as a preoperative medication in HT.
METHODS: The study was a prospective trial of 46 consecutive patients who underwent HT between January and May 2017. Patients with normal vital parameters on arrival were given Tab clonidine (0.1 mg) 30 min before starting of the procedure [Clonidine group (n = 30)]; rest were included in the control group (n = 16). Vitals were monitored every 30 min during surgery until the end. Patients were assessed for pain, level of sedation during surgery and for postoperative analgesia.
RESULTS: All patients who received clonidine, except one, were comfortable and experienced no pain throughout the duration of surgery; nine went into deep sleep. Of the 16 patients in the control group, no patients reported deep sleep, 3 felt restless, and 4 had mild pain. There were no untoward effects in both groups.
CONCLUSIONS: Our study suggests that clonidine is useful as a pre-anesthetic medication in HT. However, this is a pilot study and further larger studies are needed.
OBJECTIVE: To study efficacy of Clonidine as a preoperative medication in HT.
METHODS: The study was a prospective trial of 46 consecutive patients who underwent HT between January and May 2017. Patients with normal vital parameters on arrival were given Tab clonidine (0.1 mg) 30 min before starting of the procedure [Clonidine group (n = 30)]; rest were included in the control group (n = 16). Vitals were monitored every 30 min during surgery until the end. Patients were assessed for pain, level of sedation during surgery and for postoperative analgesia.
RESULTS: All patients who received clonidine, except one, were comfortable and experienced no pain throughout the duration of surgery; nine went into deep sleep. Of the 16 patients in the control group, no patients reported deep sleep, 3 felt restless, and 4 had mild pain. There were no untoward effects in both groups.
CONCLUSIONS: Our study suggests that clonidine is useful as a pre-anesthetic medication in HT. However, this is a pilot study and further larger studies are needed.
摘要：
背景：毛发移植（HT）对于患者和外科医生来说都是安全且有益的程序。可乐定可能是HT的良好佐剂，因为它具有镇痛作用，抗焦虑药,和镇静作用。
目的：研究可乐定作为HT术前用药的疗效。
方法：该研究是一项前瞻性试验，纳入了2017年1月至5月间接受HT的46例连续患者。到达时生命参数正常的患者在手术开始前30分钟给予Tab可乐定（0.1mg）[可乐定组（n=30）]；其余包括在对照组（n=16）中。在手术期间每30分钟监测生命体征直至结束。对患者进行疼痛评估，术中镇静水平和术后镇痛。
结果：所有接受可乐定的患者，除了一个,在整个手术期间都很舒适，没有疼痛；九人进入深度睡眠。在对照组的16名患者中，没有患者报告深度睡眠，3感到不安，和4有轻微的疼痛。两组均无不良影响。
结论：我们的研究表明，可乐定作为HT的麻醉前药物是有用的。然而,这是一项试点研究，需要进一步进行更大的研究。
目的：研究可乐定作为HT术前用药的疗效。
方法：该研究是一项前瞻性试验，纳入了2017年1月至5月间接受HT的46例连续患者。到达时生命参数正常的患者在手术开始前30分钟给予Tab可乐定（0.1mg）[可乐定组（n=30）]；其余包括在对照组（n=16）中。在手术期间每30分钟监测生命体征直至结束。对患者进行疼痛评估，术中镇静水平和术后镇痛。
结果：所有接受可乐定的患者，除了一个,在整个手术期间都很舒适，没有疼痛；九人进入深度睡眠。在对照组的16名患者中，没有患者报告深度睡眠，3感到不安，和4有轻微的疼痛。两组均无不良影响。
结论：我们的研究表明，可乐定作为HT的麻醉前药物是有用的。然而,这是一项试点研究，需要进一步进行更大的研究。
