Abstract：
Cleaning products are mixtures of many chemical ingredients that are known to contain sensitizers, disinfectants, and fragrances, as well as strong airway irritants which associated with lower respiratory tract and asthma symptoms. The aim of this study is to assess the prevalence and possible risk factors of occupational asthma and its effect on quality of life among workers in detergent and cleaning products industries in El Asher men Ramadan city. This cross-sectional study was conducted on 780 workers. All participants were personally interviewed at their workplaces and were subjected to a questionnaire regarding sociodemographic, work characteristics and asthma symptoms, clinical examination, chest X-ray, spirometer, and bronchodilator test. The prevalence of occupational asthma among the studied workers was 35.4%. Multivariate logistic regression analysis revealed that female gender [odds ratio 1.397; 95% CI 1.09-1.96], manually working participants [odds ratio 3.067; 95% CI 1.72-5.46], and history of atopy [odds ratio 1.596; 95% CI 1.09-2.33] were risk factors for development of occupational asthma. The total mean score of asthma-specific quality of life was significantly lower in asthmatic (5.10 ± 0.49) than non-asthmatic workers (5.89 ± 0.46) (P < 0.01) indicating impairment of quality of life among asthmatic group. Workers in detergent and cleaning products industry are at higher risk for developing occupational asthma that adversely affects their general health and quality of life.
摘要：
清洁产品是已知含有敏化剂的许多化学成分的混合物，消毒剂,和香水，以及与下呼吸道和哮喘症状相关的强气道刺激物。这项研究的目的是评估ElAshermen斋月市洗涤剂和清洁产品行业工人的职业性哮喘的患病率和可能的危险因素及其对生活质量的影响。这项横断面研究是对780名工人进行的。所有参与者都在他们的工作场所进行了亲自访谈，并接受了关于社会人口统计学的问卷，工作特点和哮喘症状，临床检查,胸部X光,肺活量计,和支气管扩张剂测试.研究工人中职业性哮喘的患病率为35.4％。多因素logistic回归分析显示女性性别[比值比1.397;95%CI1.09-1.96],手动工作参与者[赔率比3.067；95%CI1.72-5.46]，特应性病史[比值比1.596;95%CI1.09-2.33]是职业性哮喘发生的危险因素。哮喘患者的哮喘特异性生活质量总平均得分（5.10±0.49）明显低于非哮喘患者（5.89±0.46）（P<0.01），表明哮喘患者的生活质量受损。洗涤剂和清洁产品行业的工人患职业性哮喘的风险更高，对他们的总体健康和生活质量产生不利影响。
