METHODS: A retrospective analysis of prospectively collected data for infection cases at two separate tertiary referral institutions was performed. We included cases of long bone FRI with a retained intramedullary nail, treated with a single stage protocol of metalwork removal, debridement, local antibiotic application using the novel mould and applicator, with additional bony stabilisation and soft tissue reconstruction where required.
RESULTS: All 13 patients achieved infection remission rate with an average follow-up of 19.7 months (range 12-28). All 6 patients with infection around an unhealed fracture achieved union at an average 8 months (range 4-12) from debridement. No patients developed aseptic wound leak.
CONCLUSIONS: Antibiotic impregnated calcium sulphate can be used safely as part of a single stage treatment protocol for the treatment of long bone fracture related infection following intramedullary nailing. We have demonstrated high rates of infection remission and union, using a newly available intramedullary applicator.
方法:对两个独立的三级转诊机构的感染病例的前瞻性收集数据进行回顾性分析。
结果:所有13例患者均达到感染缓解率,平均随访时间为19.7个月(范围12-28)。
结论:抗生素浸渍硫酸钙可以安全地用作单阶段治疗方案的一部分,用于治疗髓内钉术后长骨骨折相关感染。